Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6310972 | 1.00 | BRD9 (0.42) | BRD9KDM1AMAOBDDB1CRBN | |
| SCHEMBL6310980 | 1.00 | BRD9 (0.42) | BRD9KDM1AMAOBDDB1CRBN | |
| SCHEMBL6814816 | 0.86 | KDM1A (0.50) | BRD9KDM1AMAOBEPHX2KMT2A | |
| SCHEMBL5747737 | 0.82 | KDM1A (0.43) | BRD9KDM1AMAOBEPHX2KMT2A | |
| SCHEMBL9944426 | 0.80 | NTRK1 (0.40) | KDM1ANFKB1NFKB2RELA | |
| SCHEMBL6310438 | 0.80 | KDM1A (0.41) | BRD9KDM1AMAOBEPHX2KMT2A | |
| SCHEMBL24213074 | 0.76 | GAA (0.43) | BRD9KDM1AMAOBEPHX2KMT2A | |
| SCHEMBL21057934 | 0.76 | ALDH1A1 (0.43) | MAOBDDB1CRBNL3MBTL1GAA | |
| SCHEMBL21138973 | 0.74 | ALDH1A1 (0.40) | DDB1CRBNEPHX2KMT2AMEN1 | |
| SCHEMBL21104024 | 0.74 | ALDH1A1 (0.40) | DDB1CRBNEPHX2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050043354-A1 | NK1 antagonist | PFIZER INC | 2005-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043354-A1 | NK1 antagonist | TACR2, TACR1, TAC3 | BRD9 3734/4885KDM1A 1794/4885MAOB 1849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.