Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 3/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.46 |
| ▸ | ITGAL | P20701 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6310641 | 0.88 | ITGB2 (0.48) | ITGB2ICAM1ITGALSMN1; SMN2LMNA | |
| SCHEMBL6310390 | 0.86 | ITGB2 (0.44) | ITGB2ICAM1ITGALSMN1; SMN2RAB9A | |
| SCHEMBL6309482 | 0.83 | ITGB2 (0.43) | ITGB2ICAM1ITGALSMN1; SMN2LMNA | |
| SCHEMBL5830329 | 0.79 | ITGB2 (0.70) | ITGB2ICAM1ITGALSMN1; SMN2LMNA | |
| SCHEMBL6198327 | 0.77 | ITGB2 (0.53) | ITGB2ICAM1ITGALSMN1; SMN2L3MBTL1 | |
| SCHEMBL7662359 | 0.77 | L3MBTL1 (0.50) | ITGB2ICAM1ITGALSMN1; SMN2LMNA | |
| SCHEMBL6199372 | 0.75 | ITGAL (0.49) | ITGB2ICAM1ITGALSMN1; SMN2LMNA | |
| SCHEMBL6200015 | 0.74 | MEN1 (0.42) | ITGALSMN1; SMN2LMNAMAPTRAB9A | |
| SCHEMBL6199134 | 0.74 | MEN1 (0.40) | ITGALSMN1; SMN2LMNAMAPTRAB9A | |
| SCHEMBL6199302 | 0.73 | KMT2A (0.43) | ITGB2ICAM1ITGALSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6878700-B1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-04-12 | — | — | US | claimed |
| US-6878700-B1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-04-12 | — | — | US | disclosed |
| US-6867203-B2 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-03-15 | — | — | US | disclosed |
| US-20040116518-A1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES | 2004-06-17 | — | — | US | disclosed |