Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ1 | P51787 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.39 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.39 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL630717 | 0.92 | KCNQ1 (0.42) | KCNQ1FKBP1AFKBP4FKBP5MMP1 | |
| SCHEMBL630287 | 0.90 | KCNQ1 (0.39) | KCNQ1FKBP1AFKBP4FKBP5LMNA | |
| SCHEMBL630553 | 0.89 | KCNQ1 (0.49) | KCNQ1FKBP1AFKBP4FKBP5MMP1 | |
| SCHEMBL1381826 | 0.89 | KCNQ1 (0.49) | KCNQ1FKBP1AFKBP4FKBP5MMP1 | |
| SCHEMBL629871 | 0.82 | KCNQ1 (0.48) | KCNQ1FKBP1AFKBP4FKBP5MMP1 | |
| SCHEMBL1384421 | 0.82 | KCNQ1 (0.48) | KCNQ1FKBP1AFKBP4FKBP5MMP1 | |
| SCHEMBL631450 | 0.82 | KCNQ1 (0.36) | KCNQ1FKBP1AFKBP4FKBP5MMP1 | |
| SCHEMBL630557 | 0.82 | ITGB1 (0.53) | KCNQ1FKBP1AFKBP4FKBP5LMNA | |
| SCHEMBL630558 | 0.82 | ITGB1 (0.53) | KCNQ1FKBP1AFKBP4FKBP5LMNA | |
| SCHEMBL630706 | 0.81 | KCNQ1 (0.46) | KCNQ1FKBP1AFKBP4FKBP5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778637-B1 | FKBP-binding composition and pharmaceutical use thereof | AVENTIS PHARMA INC (US) | 2012-02-22 | — | — | EP | claimed |