Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ1 | P51787 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.35 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | YAP1 | P46937 | 2/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL631041 | 0.91 | ELOVL6 (0.40) | KCNQ1MMP1ADAM17FKBP1AFKBP4 | |
| SCHEMBL630003 | 0.91 | KCNQ1 (0.43) | KCNQ1MMP1ADAM17FKBP1AFKBP4 | |
| SCHEMBL630287 | 0.84 | KCNQ1 (0.39) | KCNQ1UTS2RFKBP1AFKBP4FKBP5 | |
| SCHEMBL13225612 | 0.83 | ITGB1 (0.41) | KCNQ1MMP1ADAM17FKBP1AFKBP4 | |
| SCHEMBL631137 | 0.82 | KCNQ1 (0.41) | KCNQ1MMP1ADAM17FKBP1AFKBP4 | |
| SCHEMBL630717 | 0.81 | KCNQ1 (0.42) | KCNQ1MMP1ADAM17FKBP1AFKBP4 | |
| SCHEMBL1383737 | 0.81 | KCNQ1 (0.45) | KCNQ1MMP1ADAM17FKBP1AFKBP4 | |
| SCHEMBL630110 | 0.81 | KCNQ1 (0.45) | KCNQ1MMP1ADAM17FKBP1AFKBP4 | |
| SCHEMBL630706 | 0.80 | KCNQ1 (0.46) | KCNQ1FKBP1AFKBP4FKBP5KMT2A | |
| SCHEMBL631454 | 0.76 | BDKRB1 (0.45) | KCNQ1UTS2RYAP1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778637-B1 | FKBP-binding composition and pharmaceutical use thereof | AVENTIS PHARMA INC (US) | 2012-02-22 | — | — | EP | claimed |