Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6318775 | 0.82 | NPSR1 (0.45) | NPSR1NPC1RAB9APPARGHPGD | |
| SCHEMBL6312483 | 0.82 | NPSR1 (0.48) | NPSR1NPC1RAB9AHPGDLMNA | |
| SCHEMBL20797121 | 0.80 | LMNA (0.44) | HPGDLMNACA1L3MBTL1ALDH1A1 | |
| SCHEMBL6393785 | 0.79 | NPSR1 (0.46) | NPSR1PPARGHPGDLMNACA1 | |
| SCHEMBL6314192 | 0.78 | NPSR1 (0.48) | NPSR1NPC1RAB9AHPGDPOLB | |
| SCHEMBL1520287 | 0.78 | NPC1 (0.69) | NPC1RAB9AHPGDPOLBSMN1; SMN2 | |
| SCHEMBL20448911 | 0.74 | GAA (0.47) | RAB9APOLBSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL30525000 | 0.74 | KMT2A (0.61) | NPSR1HPGDLMNAMAPTALDH1A1 | |
| SCHEMBL28900428 | 0.73 | ACE (0.47) | NPSR1LMNACA1CA2L3MBTL1 | |
| SCHEMBL6320179 | 0.73 | NPC1 (0.43) | NPSR1NPC1RAB9AHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014810-A1 | Use of substituted 2 phenylbenzimidazoles as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014810-A1 | Use of substituted 2 phenylbenzimidazoles as medicaments | GLP1R, GIPR, GCGR | NPSR1 198/4885NPC1 2833/4885RAB9A 4571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.