Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20797165 | 0.82 | LMNA (0.46) | KMT2AALDH1A1L3MBTL1HPGDTP53 | |
| SCHEMBL6312483 | 0.81 | NPSR1 (0.48) | NPSR1KMT2AMEN1HIF1AALDH1A1 | |
| SCHEMBL6393785 | 0.79 | NPSR1 (0.46) | NPSR1KMT2AMEN1HIF1AALDH1A1 | |
| SCHEMBL6318775 | 0.78 | NPSR1 (0.45) | NPSR1KMT2AMEN1HIF1AALDH1A1 | |
| SCHEMBL6311787 | 0.78 | NPSR1 (0.45) | NPSR1KMT2AMEN1HIF1AALDH1A1 | |
| SCHEMBL9951667 | 0.77 | NPSR1 (0.67) | NPSR1KMT2AMEN1HIF1AALDH1A1 | |
| SCHEMBL3199672 | 0.77 | NPSR1 (0.67) | NPSR1KMT2AMEN1HIF1AALDH1A1 | |
| SCHEMBL1917217 | 0.75 | HTT (0.44) | KMT2AALDH1A1HPGDTP53TSHR | |
| SCHEMBL23039128 | 0.75 | L3MBTL1 (0.44) | KMT2AALDH1A1L3MBTL1HPGDHTT | |
| SCHEMBL23039037 | 0.74 | TAS1R3 (0.51) | ALDH1A1L3MBTL1HPGDHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014810-A1 | Use of substituted 2 phenylbenzimidazoles as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014810-A1 | Use of substituted 2 phenylbenzimidazoles as medicaments | GLP1R, GIPR, GCGR | NPSR1 198/4885KMT2A 2473/4885MEN1 733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.