Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 14/20 | 0.46 |
| ▸ | RARG | P13631 | 8/20 | 0.46 |
| ▸ | RXRB | P28702 | 5/20 | 0.46 |
| ▸ | RXRG | P48443 | 5/20 | 0.46 |
| ▸ | RARA | P10276 | 4/20 | 0.46 |
| ▸ | RARB | P10826 | 4/20 | 0.46 |
| ▸ | PPARG | P37231 | 8/20 | 0.38 |
| ▸ | HNF4A | P41235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6450239 | 1.00 | RXRA (0.46) | RXRARARGRXRBRXRGRARA | |
| SCHEMBL6297007 | 0.92 | RXRA (0.56) | RXRARARGRXRBRXRGRARA | |
| SCHEMBL6296485 | 0.90 | RXRA (0.48) | RXRARARGRXRBRXRGRARA | |
| SCHEMBL6285209 | 0.83 | RXRA (0.68) | RXRARARGRXRBRXRGRARA | |
| SCHEMBL6283376 | 0.82 | RXRA (0.59) | RXRARARGRXRBRXRGRARA | |
| SCHEMBL7602498 | 0.78 | RXRA (0.41) | RXRARARGRXRBRXRGRARA | |
| SCHEMBL6275714 | 0.78 | TSHR (0.47) | RXRARARGRXRBRXRGRARA | |
| SCHEMBL6279295 | 0.77 | RXRA (0.48) | RXRARARGRXRBRXRGRARA | |
| SCHEMBL6279289 | 0.77 | RXRA (0.48) | RXRARARGRXRBRXRGRARA | |
| SCHEMBL6283134 | 0.77 | HNF4A (0.40) | RXRARARGRXRBRXRGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887896-B1 | 7-[(7-Alkoxy)-chrom-3-en-6-yl]-heptatrienoic acid and 7-[(3-alkoxy)-5,6-dihydronaphthalen-2-yl]-heptatrienoic acid derivatives having serum glucose reducing activity | ALLERGAN, INC. (US) | 2005-05-03 | — | — | US | disclosed |