Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29221545 | 1.00 | TSHR (0.46) | TSHRLMNACHRM2CHRM4CHRM5 | |
| SCHEMBL30678661 | 1.00 | TSHR (0.46) | TSHRLMNACHRM2CHRM4CHRM5 | |
| SCHEMBL5531906 | 1.00 | TSHR (0.46) | TSHRLMNACHRM2CHRM4CHRM5 | |
| SCHEMBL499368 | 0.93 | — | — | |
| Ammonia Solution, Strong SCHEMBL27654016 | 0.90 | — | — | |
| SCHEMBL4696456 | 0.89 | TSHR (0.42) | TSHRLMNACHRM2CHRM4CHRM5 | |
| SCHEMBL24835739 | 0.87 | TSHR (0.50) | TSHRLMNACHRM2CHRM4CHRM5 | |
| SCHEMBL31591142 | 0.87 | TSHR (0.50) | TSHRLMNACHRM2CHRM4CHRM5 | |
| SCHEMBL30552236 | 0.87 | TSHR (0.50) | TSHRLMNACHRM2CHRM4CHRM5 | |
| SCHEMBL29009364 | 0.86 | ALOX15 (0.41) | TSHRLMNACHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323876-A | Grease composition comprising inorganic fullerene-like particles | 纳米技术工业解决方案公司 | 2023-06-23 | — | — | CN | disclosed |
| EP-3642272-A1 | FILMS WITH A PRIMER LAYER CONTAINING SILICA NANOPARTICLES MODIFIED BY AN ORGANIC SILANE | 3M Innovative Properties Company (US) | 2020-04-29 | — | — | EP | disclosed |
| WO-2018234916-A1 | FILMS WITH A PRIMER LAYER CONTAINING SILICA NANOPARTICLES MODIFIED BY AN ORGANIC SILANE | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-12-27 | — | — | WO | disclosed |
| US-10017527-B2 | KLK4 inhibitors | UNIVERSITEIT ANTWERPEN (BE) | 2018-07-10 | — | — | US | disclosed |
| EP-3317090-A1 | INSULATED GLAZING UNITS AND MICROOPTICAL LAYER INCLUDING MICROSTRUCTURED ANISOTROPIC DIFFUSER AND METHODS | 3M Innovative Properties Company (US) | 2018-05-09 | — | — | EP | disclosed |
| CN-104540900-B | Antifouling hard and antifouling hard precursor | 3M创新有限公司 | 2017-11-17 | — | — | CN | disclosed |
| EP-1836128-B1 | ZIRCONIA PARTICLES | 3M INNOVATIVE PROPERTIES CO (US) | 2017-10-11 | — | — | EP | disclosed |
| CN-104619790-B | Anti-reflective hard coat and anti-reflective article | 3M创新有限公司 | 2017-05-17 | — | — | CN | disclosed |
| US-20170101427-A1 | NOVEL KLK4 INHIBITORS | UNIVERSITEIT ANTWERPEN (BE) | 2017-04-13 | — | — | US | disclosed |
| CN-103168257-B | There is porous low-index layer and there is the optical element of protective layer | 3M创新有限公司 | 2017-03-01 | — | — | CN | disclosed |
| WO-2015144933-A1 | NOVEL KLK4 INHIBITORS | UNIVERSITEIT ANTWERPEN (BE) | 2015-10-01 | — | — | WO | disclosed |
| EP-2861678-A1 | COATING COMPOSITIONS COMPRISING POLYMERIZABLE NON-IONIC SURFACTANT EXHIBITING REDUCED FINGERPRINT VISIBILITY | 3M Innovative Properties Company (US) | 2015-04-22 | — | — | EP | disclosed |
| EP-2798022-A1 | CLEANABLE ARTICLES AND METHODS FOR MAKING AND USING SAME | 3M Innovative Properties Company (US) | 2014-11-05 | — | — | EP | disclosed |
| WO-2014133799-A1 | LAMINATION TRANSFER FILMS FOR FORMING EMBEDDED NANOSTRUCTURES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-09-04 | — | — | WO | disclosed |
| WO-2013191822-A1 | COATING COMPOSITIONS COMPRISING POLYMERIZABLE NON-IONIC SURFACTANT EXHIBITING REDUCED FINGERPRINT VISIBILITY | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-12-27 | — | — | WO | disclosed |
| EP-2655525-A2 | COATING COMPOSITIONS COMPRISING NON-IONIC SURFACTANT EXHIBITING REDUCED FINGERPRINT VISIBILITY | 3M Innovative Properties Company (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2013102099-A1 | CLEANABLE ARTICLES AND METHODS FOR MAKING AND USING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-07-04 | — | — | WO | disclosed |
| WO-2012087661-A2 | COATING COMPOSITIONS COMPRISING NON-IONIC SURFACTANT EXHIBITING REDUCED FINGERPRINT VISIBILITY | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-06-28 | — | — | WO | disclosed |
| EP-2419267-A1 | RETROREFLECTIVE ARTICLES INCLUDING PRINTED AREAS | 3M Innovative Properties Company (US) | 2012-02-22 | — | — | EP | disclosed |
| WO-2010121056-A1 | RETROREFLECTIVE ARTICLES INCLUDING PRINTED AREAS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2010-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10017527-B2 | KLK4 inhibitors | KLK4, KLK3, KLK1 | TSHR 3699/4885LMNA 670/4885CHRM2 1647/4885 |
| US-20170101427-A1 | NOVEL KLK4 INHIBITORS | KLK4, KLK3, KLK1 | TSHR 3647/4885LMNA 741/4885CHRM2 1473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.