SCHEMBL631254

SCHEMBL631254

O=C(O)CC(F)(F)CF

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25772273 0.84 ACLY (0.48)
SCHEMBL3955843 0.78 OR51E2 (0.35)
SCHEMBL27291903 0.74
SCHEMBL11573860 0.74
SCHEMBL347950 0.74
SCHEMBL14637636 0.74
SCHEMBL1032090 0.74
SCHEMBL8144771 0.74 TET2 (0.52)
SCHEMBL4325199 0.73 ALDH1A1 (0.41)
SCHEMBL10269458 0.72 HMGCR (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3523280-B1 PROCESSES AND INTERMEDIATES FOR PREPARING A BTK INHIBITOR JANSSEN PHARMACEUTICA NV (BE) 2026-03-11 EP claimed
US-11735771-B2 Electrolyte solution and electrochemical device using the same NINGDE AMPEREX TECHNOLOGY LIMITED (CN) 2023-08-22 US claimed
EP-3915168-A1 ELECTROLYTE SOLUTION AND ELECTROCHEMICAL DEVICE USING THE SAME Ningde Amperex Technology Ltd. (CN) 2021-12-01 EP claimed
EP-3318554-B1 METHOD FOR PRODUCING PEST CONTROL AGENT MEIJI SEIKA PHARMA CO LTD (JP) 2021-11-03 EP claimed
US-20210257662-A1 ELECTROLYTE SOLUTION AND ELECTROCHEMICAL DEVICE USING THE SAME NINGDE AMPEREX TECHNOLOGY LIMITED (CN) 2021-08-19 US claimed
EP-2432791-B1 A CHEMO-ENZYMATIC APPROACH TO THE SYNTHESIS OF PIMECROLIMUS EUTICALS SPA (IT) 2015-07-08 EP claimed
EP-2457921-B1 AUREOLIC ACID DERIVATIVES, THE METHOD FOR PREPARATION THEREOF AND THE USES THEREOF ENTRECHEM S L (ES) 2014-03-19 EP claimed
US-20260149042-A1 IONIC LIQUID, ELECTROLYTE FOR SECONDARY BATTERY COMPRISING THE IONIC LIQUID, AND SECONDARY BATTERY COMPRISING THE SAME SK ON CO., LTD. (KR) 2026-05-28 US disclosed
US-11735771-B2 Electrolyte solution and electrochemical device using the same NINGDE AMPEREX TECHNOLOGY LIMITED (CN) 2023-08-22 US disclosed
EP-3915168-A1 ELECTROLYTE SOLUTION AND ELECTROCHEMICAL DEVICE USING THE SAME Ningde Amperex Technology Ltd. (CN) 2021-12-01 EP disclosed
US-20210289794-A1 COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-09-23 US disclosed
US-20210257662-A1 ELECTROLYTE SOLUTION AND ELECTROCHEMICAL DEVICE USING THE SAME NINGDE AMPEREX TECHNOLOGY LIMITED (CN) 2021-08-19 US disclosed
EP-1562603-B3 NOVEL MEDICAMENTS FOR THE TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASES BOEHRINGER INGELHEIM PHARMA (DE) 2014-01-08 EP disclosed
US-20040121435-A1 Biocatalytic preparation of enantiomerically enriched aminopentanenitrile PFIZER INC. 2004-06-24 US disclosed
WO-2004045618-A2 NOVEL MEDICAMENTS FOR THE TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASES BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2004-06-03 WO disclosed
US-20030134900-A1 Process for the preparation of dihydroxy esters and derivatives thereof ASTRAZENECA UK LIMITED (GB) 2003-07-17 US disclosed
EP-1282719-A1 PROCESS FOR THE PREPARATION OF DIHYDROXY ESTERS AND DERIVATIVES THEREOF Avecia Limited (GB) 2003-02-12 EP disclosed
WO-2001085975-A1 PROCESS FOR THE PREPARATION OF DIHYDROXY ESTERS AND DERIVATIVES THEREOF AVECIA LIMITED (GB) 2001-11-15 WO disclosed
US-5684149-A CYCLIC ALKYLENETETRAMINES WITH METALS AS CATALYSTS RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1997-11-04 US disclosed
EP-0754700-A2 Labelling and detection of nucleic acids Cruachem Limited (GB) 1997-01-22 EP disclosed