Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.63 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.63 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.60 |
| ▸ | BCHE | P06276 | 6/20 | 0.59 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | RXRA | P19793 | 1/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17912878 | 0.96 | MAPT (0.66) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL18623128 | 0.93 | HTR1A (0.68) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL21300617 | 0.89 | BCHE (0.67) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL30445162 | 0.84 | HTR1A (0.58) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL11019947 | 0.84 | HTR1A (0.58) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL30416387 | 0.84 | HTR1A (0.74) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL791853 | 0.84 | HTR1A (0.74) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL6194328 | 0.82 | ATM (0.57) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| Ammonia Solution, Strong SCHEMBL2063054 | 0.82 | HTR1A (0.72) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL12843212 | 0.82 | BCHE (0.60) | HTR1AADRA1DADRA1AADRA1BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768746-A | Method for synthesizing chiral 2-amido benzhydrol by iridium catalysis | 中国科学院大连化学物理研究所 | 2023-09-19 | — | — | CN | disclosed |
| US-20230263155-A1 | 5-(1H-INDOL-3-YL)-OXAZOLE, -OXADIAZOLE AND -FURAN DERIVATIVES AS ENHANCERS OF SPERM MOTILITY | SPERMATECH AS (NO) | 2023-08-24 | — | — | US | disclosed |
| US-6939874-B2 | Substituted pyrimidinyl derivatives and methods of use | AMGEN INC. (US) | 2005-09-06 | — | — | US | disclosed |
| US-20040063705-A1 | Substituted pyrimidinyl derivatives and methods of use | AMGEN INC. | 2004-04-01 | — | — | US | disclosed |
| US-6235746-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATIVE AGENT | CELLTECH THERAPEUTICS, LIMITED (GB) | 2001-05-22 | — | — | US | disclosed |
| US-5958935-A | Substituted 2-anilinopyrimidines useful as protein kinase inhibitors | CELLTECH THERAPEUTICS LIMITED (GB) | 1999-09-28 | — | — | US | disclosed |
| EP-0862560-A1 | SUBSTITUTED 2-ANILINOPYRIMIDINES USEFUL AS PROTEIN KINASE INHIBITORS | CELLTECH THERAPEUTICS LIMITED (GB) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997019065-A1 | SUBSTITUTED 2-ANILINOPYRIMIDINES USEFUL AS PROTEIN KINASE INHIBITORS | CELLTECH THERAPEUTICS LIMITED (GB) | 1997-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230263155-A1 | 5-(1H-INDOL-3-YL)-OXAZOLE, -OXADIAZOLE AND -FURAN DERIVATIVES AS ENHANCERS OF SPERM MOTILITY | NR5A1, NR1I3, NR5A2 | HTR1A 167/4885ADRA1D 75/4885ADRA1A 54/4885 |
| US-20040063705-A1 | Substituted pyrimidinyl derivatives and methods of use | DPYD, TYMP, TPMT | HTR1A 2218/4885ADRA1D 2898/4885ADRA1A 2633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.