Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | LIPE | Q05469 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11019947 | 1.00 | HTR1A (0.58) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL1952684 | 0.88 | HTR1A (0.63) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL17912878 | 0.88 | MAPT (0.66) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL3757832 | 0.87 | BCHE (0.58) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL6312645 | 0.84 | HTR1A (0.63) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL28941896 | 0.82 | HTR1A (0.57) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL18623128 | 0.81 | HTR1A (0.68) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL6586809 | 0.81 | LIPE (0.71) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL6356278 | 0.80 | MAPT (0.60) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| Formic Acid SCHEMBL28842421 | 0.80 | BCHE (0.56) | HTR1AADRA1DADRA1AADRA1BL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116265458-A | Benzothiophene derivative, preparation method and application thereof | 中国科学院上海药物研究所 | 2023-06-20 | — | — | CN | disclosed |