Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 4/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4310484 | 0.85 | ACHE (0.55) | KDM4EALDH1A1HPGDHSD17B10ACHE | |
| SCHEMBL24801284 | 0.81 | CYP2A6 (0.43) | KDM4EALDH1A1HPGDHSD17B10ACHE | |
| SCHEMBL29919905 | 0.79 | NQO1 (0.67) | KDM4EALDH1A1HPGDHSD17B10ACHE | |
| SCHEMBL8393507 | 0.79 | NQO1 (0.67) | KDM4EALDH1A1HPGDHSD17B10ACHE | |
| SCHEMBL29869216 | 0.78 | CYP1A2 (0.57) | KDM4EALDH1A1HPGDHSD17B10ACHE | |
| SCHEMBL1402278 | 0.78 | NQO1 (0.50) | KDM4EALDH1A1HPGDHSD17B10ACHE | |
| SCHEMBL8157352 | 0.78 | CYP1A2 (0.59) | KDM4EALDH1A1HPGDHSD17B10ACHE | |
| SCHEMBL19208975 | 0.78 | NQO2 (0.50) | KDM4EALDH1A1HPGDHSD17B10NQO1 | |
| SCHEMBL24773765 | 0.78 | ACHE (0.53) | KDM4EALDH1A1HPGDHSD17B10ACHE | |
| SCHEMBL443271 | 0.78 | CYP1A2 (0.57) | KDM4EALDH1A1HPGDHSD17B10ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110678532-B | Organic photochromic dye and use thereof for dye sensitized solar cells | 法国原子能源和替代能源委员会 | 2023-11-03 | — | — | CN | disclosed |
| US-20230354692-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-11-02 | — | — | US | disclosed |
| US-20230354692-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-11-02 | — | — | US | disclosed |
| US-20230354692-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-11-02 | — | — | US | disclosed |
| US-11778897-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2023-10-03 | — | — | US | disclosed |
| US-11778897-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2023-10-03 | — | — | US | disclosed |
| US-11778897-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2023-10-03 | — | — | US | disclosed |
| EP-3609976-B1 | ORGANIC PHOTOCHROMIC DYE AND USES THEREOF FOR DYE SENSITIZED SOLAR CELLS | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2022-08-24 | — | — | EP | disclosed |
| CN-107406414-B | (piperidin-3-yl) (naphthalen-2-yl) methanone derivatives as inhibitors of histone demethylase KDM2B for the treatment of cancer | 基因泰克公司 | 2022-04-19 | — | — | CN | disclosed |
| US-11248123-B2 | Organic photochromic dye and uses thereof for dye sensitized solar cells | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2022-02-15 | — | — | US | disclosed |
| CN-1312151-C | (imidazol-1-yl-methyl)-pyridazine as NMDA receptor blocker | HOFFMANN LA ROCHE (CH) | 2007-04-25 | — | — | CN | disclosed |
| US-20050272786-A1 | Naphthyl benzoxazoles and benzisoxazoles as estrogenic agents | WYETH (US) | 2005-12-08 | — | — | US | disclosed |
| US-6960607-B2 | Naphthyl benzoxazoles and benzisoxazoles as estrogenic agents | WYETH (US) | 2005-11-01 | — | — | US | disclosed |
| CN-1653062-A | (imidazol-1-yl-methyl)-pyridazine as NMDA receptor blocker | HOFFMANN LA ROCHE (CH) | 2005-08-10 | — | — | CN | disclosed |
| US-20030171412-A1 | Naphthyl benzoxazoles and benzisoxazoles as estrogenic agents | WYETH | 2003-09-11 | — | — | US | disclosed |
| EP-0416038-B1 | NOVEL CHEMILUMINESCENT FUSED POLYCYCLIC RING-CONTAINING 1,2-DIOXETANES AND ASSAYS IN WHICH THEY ARE USED | TROPIX INC (US) | 1997-03-26 | — | — | EP | disclosed |
| EP-0416038-A4 | NOVEL CHEMILUMINESCENT FUSED POLYCYCLIC RING-CONTAINING 1,2-DIOXETANES AND ASSAYS IN WHICH THEY ARE USED | — | 1992-02-26 | — | — | EP | disclosed |
| EP-0416038-A1 | NOVEL CHEMILUMINESCENT FUSED POLYCYCLIC RING-CONTAINING 1,2-DIOXETANES AND ASSAYS IN WHICH THEY ARE USED. | TROPIX INC (US) | 1991-03-13 | — | — | EP | disclosed |
| US-4952707-A | DECOMPOSITION TO LIGHT EMITTING FLUOROPHORE; ANALYSIS | TROPIX, INC. (US) | 1990-08-28 | — | — | US | disclosed |
| WO-1990000164-A1 | NOVEL CHEMILUMINESCENT FUSED POLYCYCLIC RING-CONTAINING 1,2-DIOXETANES AND ASSAYS IN WHICH THEY ARE USED | TROPIX, INC. (US) | 1990-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11778897-B2 | Organic electroluminescent materials and devices | LIFR, LBR, ZFR | KDM4E 1788/4885ALDH1A1 2258/4885HPGD 4453/4885 |
| US-20030171412-A1 | Naphthyl benzoxazoles and benzisoxazoles as estrogenic agents | ESR1, ESR2, ESRRA | KDM4E 1150/4885ALDH1A1 702/4885HPGD 2180/4885 |
| US-20050272786-A1 | Naphthyl benzoxazoles and benzisoxazoles as estrogenic agents | ESR1, ESRRA, ESR2 | KDM4E 973/4885ALDH1A1 538/4885HPGD 1972/4885 |
| US-20230354692-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | LIFR, LBR, ZFR | KDM4E 1788/4885ALDH1A1 2258/4885HPGD 4453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.