Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7507906 | 0.78 | ALDH1A1 (0.61) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL5749705 | 0.74 | ALDH1A1 (0.56) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL1420797 | 0.72 | ALDH1A1 (1.00) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL26437832 | 0.71 | ALDH1A1 (0.36) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL5107204 | 0.71 | ALDH1A1 (0.52) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL3153578 | 0.70 | ALDH1A1 (0.56) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL5565469 | 0.70 | ALDH1A1 (0.51) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL1101901 | 0.70 | HRH4 (0.40) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL17371154 | 0.69 | MAPT (0.48) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL11629062 | 0.68 | ALDH1A1 (0.59) | ALDH1A1MAPTRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6958330-B1 | Polycyclic α-amino-ε-caprolactams and related compounds | ELAN PHARMACEUTICALS, INC. (US) | 2005-10-25 | — | — | US | disclosed |