SCHEMBL7507906

SCHEMBL7507906

CC1=Nc2ccccc2NC(=O)C1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.61
MAPT P10636 8/20 0.55
RAB9A P51151 4/20 0.55
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
NPC1 O15118 3/20 0.55
CASP3 P42574 1/20 0.55
SENP8 Q96LD8 1/20 0.55
SENP7 Q9BQF6 1/20 0.55
SENP6 Q9GZR1 1/20 0.55
TP53 P04637 1/20 0.54
SMN1; SMN2 Q16637 3/20 0.52
KDM4E B2RXH2 3/20 0.51
LMNA P02545 2/20 0.51
HTT P42858 1/20 0.51
POLB P06746 1/20 0.49
ALOX15 P16050 1/20 0.49
BRCA1 P38398 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
HSD17B10 Q99714 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6313162 0.78 ALDH1A1 (0.56) ALDH1A1MAPTRAB9AMEN1KMT2A
SCHEMBL5749705 0.78 ALDH1A1 (0.56) ALDH1A1MAPTRAB9AMEN1KMT2A
SCHEMBL11626115 0.77 RAB9A (0.61) ALDH1A1MAPTRAB9AMEN1KMT2A
SCHEMBL1420797 0.76 ALDH1A1 (1.00) ALDH1A1MAPTRAB9AMEN1KMT2A
SCHEMBL1424406 0.75 ALDH1A1 (0.72) ALDH1A1RAB9ANPC1TP53SMN1; SMN2
SCHEMBL5107204 0.74 ALDH1A1 (0.52) ALDH1A1MAPTRAB9AMEN1KMT2A
SCHEMBL3153578 0.74 ALDH1A1 (0.56) ALDH1A1MAPTRAB9AMEN1KMT2A
SCHEMBL19846240 0.74 RAB9A (0.38) ALDH1A1MAPTRAB9AMEN1KMT2A
SCHEMBL5565469 0.73 ALDH1A1 (0.51) ALDH1A1MAPTRAB9AMEN1KMT2A
SCHEMBL14874962 0.72 MAPT (0.53) ALDH1A1MAPTRAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11744152-B2 Benzimidazo[1,2-a]benzimidazole derivatives for electronic applications UDC IRELAND LIMITED (IE) 2023-08-29 US disclosed
US-11744152-B2 Benzimidazo[1,2-a]benzimidazole derivatives for electronic applications UDC IRELAND LIMITED (IE) 2023-08-29 US disclosed
US-20210083200-A1 Benzimidazo[1,2-a]Benzimidazole Derivatives for Electronic Applications UDC IRELAND LTD (IE) 2021-03-18 US disclosed
EP-3318566-B1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS UDC IRELAND LTD (IE) 2020-06-24 EP disclosed
EP-3328860-B1 PROCESS FOR THE PREPARATION OF BENZIMIDAZO[1,2-A]BENZIMIDAZOLES UDC IRELAND LTD (IE) 2020-03-04 EP disclosed
US-10570136-B2 Process for the preparation of benzimidazo[1,2-a] benzimidazoles UDC IRELAND LIMITED (IE) 2020-02-25 US disclosed
US-10431750-B2 4H-imidazo[1,2-a]imidazoles for electronic applications UDC IRELAND LIMITED (IE) 2019-10-01 US disclosed
US-20190273211-A1 4H-Imidazo[1,2-a]imidazoles for Electronic Applications UDC IRELAND LTD (IE) 2019-09-05 US disclosed
US-20190131547-A1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS UDC IRELAND LTD (IE) 2019-05-02 US disclosed
US-10249827-B2 Azadibenzofurans for electronic applications UDC IRELAND LIMITED (IE) 2019-04-02 US disclosed
US-20140252280-A1 4H-IMIDAZO[1,2-A]IMIDAZOLES FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2014-09-11 US disclosed
US-20140252280-A1 4H-IMIDAZO[1,2-A]IMIDAZOLES FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2014-09-11 US disclosed
WO-2014044722-A1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2014-03-27 WO disclosed
WO-2013068376-A1 4H-IMIDAZO[1,2-A]IMIDAZOLES FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2013-05-16 WO disclosed
WO-2012130709-A1 4H-IMIDAZO[1,2-A]IMIDAZOLES FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2012-10-04 WO disclosed
US-20120241681-A1 4H-Imidazo[1,2-a]imidazoles for Electronic Applications BASF SE (DE) 2012-09-27 US disclosed
US-20120241681-A1 4H-Imidazo[1,2-a]imidazoles for Electronic Applications BASF SE (DE) 2012-09-27 US disclosed
EP-0757681-B1 CONDENSED HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE AS GnRH ANTAGONISTS TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2002-09-18 EP disclosed
US-5834463-A CONTROLLING FERTILITY, MENSTRUAL CYCLES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-11-10 US disclosed
WO-1995029900-A1 CONDENSED HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE AS GnRH ANTAGONISTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-11-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210083200-A1 Benzimidazo[1,2-a]Benzimidazole Derivatives for Electronic Applications PAICS, EIF4A1, ECI1 ALDH1A1 122/4885MAPT 2317/4885RAB9A 1588/4885
US-20120241681-A1 4H-Imidazo[1,2-a]imidazoles for Electronic Applications EIF4A1, ITPR2, ITPR1 ALDH1A1 355/4885MAPT 1159/4885RAB9A 764/4885
US-10570136-B2 Process for the preparation of benzimidazo[1,2-a] benzimidazoles CYP3A4, CYP2C19, CYP1B1 ALDH1A1 57/4885MAPT 2400/4885RAB9A 2804/4885
US-10431750-B2 4H-imidazo[1,2-a]imidazoles for electronic applications EIF4A1, ITPR2, ITPR1 ALDH1A1 355/4885MAPT 1159/4885RAB9A 764/4885
US-20190273211-A1 4H-Imidazo[1,2-a]imidazoles for Electronic Applications PAH, NISCH, KCNH1 ALDH1A1 405/4885MAPT 1665/4885RAB9A 447/4885
US-20190131547-A1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS AZI2, BRPF1, CCNB1 ALDH1A1 547/4885MAPT 4528/4885RAB9A 2061/4885
US-11744152-B2 Benzimidazo[1,2-a]benzimidazole derivatives for electronic applications PAICS, EIF4A1, ECI1 ALDH1A1 122/4885MAPT 2317/4885RAB9A 1588/4885
US-10249827-B2 Azadibenzofurans for electronic applications AZI2, BRPF1, CCNB1 ALDH1A1 547/4885MAPT 4528/4885RAB9A 2061/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.