Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | CASR | P41180 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6533202 | 0.87 | CA1 (0.56) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL1865894 | 0.86 | CYP4F2 (0.50) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL11159467 | 0.85 | SMN1; SMN2 (0.57) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL9678668 | 0.85 | LMNA (0.57) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL5095002 | 0.84 | CA12 (0.46) | MEN1KMT2AALDH1A1MAPTHTT | |
| Benzene SCHEMBL27873122 | 0.84 | CA1 (0.76) | MEN1KMT2AALDH1A1MAPTHTT | |
| Ethyl Benzoate SCHEMBL28522459 | 0.82 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| Ethyl Benzoate SCHEMBL28426605 | 0.82 | LMNA (0.58) | MEN1KMT2AALDH1A1MAPTHTT | |
| Ethyl Benzoate SCHEMBL28426606 | 0.82 | LMNA (0.58) | MEN1KMT2AALDH1A1MAPTHTT | |
| Ethyl Benzoate SCHEMBL25388294 | 0.82 | LMNA (0.70) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6899830-B1 | Method for producing Grignard compounds | BASF (DE) | 2005-05-31 | — | — | US | disclosed |
| WO-2000048993-A1 | ARYLAMINOALKYLAMIDES | NOVARTIS AG (CH) | 2000-08-24 | — | — | WO | disclosed |