Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11579276 | 0.94 | ALDH1A1 (0.67) | ALDH1A1HIF1AVCAM1MAPTTDP1 | |
| Sulfur Dioxide SCHEMBL21643667 | 0.88 | ALDH1A1 (0.60) | ALDH1A1HIF1AVCAM1MAPTTDP1 | |
| SCHEMBL6314467 | 0.86 | ALDH1A1 (0.58) | ALDH1A1HIF1AVCAM1MAPTTDP1 | |
| SCHEMBL25247338 | 0.85 | TDP1 (0.76) | ALDH1A1HIF1AVCAM1MAPTTDP1 | |
| SCHEMBL31109079 | 0.85 | TDP1 (0.76) | ALDH1A1HIF1AVCAM1MAPTTDP1 | |
| SCHEMBL6319435 | 0.85 | ALDH1A1 (0.56) | ALDH1A1HIF1AVCAM1MAPTTDP1 | |
| SCHEMBL2650363 | 0.85 | CRHBP (0.58) | ALDH1A1HIF1AVCAM1MAPTTDP1 | |
| SCHEMBL3497277 | 0.85 | ALDH1A1 (0.56) | ALDH1A1HIF1AVCAM1MAPTTDP1 | |
| SCHEMBL14956676 | 0.82 | VCAM1 (0.74) | ALDH1A1HIF1AVCAM1MAPTTDP1 | |
| SCHEMBL6313832 | 0.82 | ALDH1A1 (0.53) | ALDH1A1HIF1AVCAM1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014810-A1 | Use of substituted 2 phenylbenzimidazoles as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014810-A1 | Use of substituted 2 phenylbenzimidazoles as medicaments | GLP1R, GIPR, GCGR | ALDH1A1 1506/4885HIF1A 489/4885VCAM1 3352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.