Sugi Predict

Sugi Predict / Compounds / SCHEMBL6313496

SCHEMBL6313496

SCHEMBL6313496

CCCCC(Oc1ccc(C(C)(C)CC)cc1C(C)(C)CC)C(=O)Cl

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 6/20 0.49
▸ NPSR1 Q6W5P4 6/20 0.49
▸ SMN1; SMN2 Q16637 5/20 0.49
▸ MEN1 O00255 4/20 0.49
▸ KMT2A Q03164 4/20 0.49
▸ ALDH1A1 P00352 1/20 0.49
▸ MAPT P10636 4/20 0.41
▸ HTT P42858 3/20 0.41
▸ UBE2N P61088 2/20 0.41
▸ GLA P06280 1/20 0.41
▸ MITF O75030 1/20 0.41
▸ RAB9A P51151 3/20 0.40
▸ RAD52 P43351 2/20 0.40
▸ APAF1 O14727 1/20 0.40
▸ HSP90AA1 P07900 1/20 0.40
▸ NOD2 Q9HC29 1/20 0.40
▸ STAT3 P40763 1/20 0.38
▸ RCE1 Q9Y256 1/20 0.38
▸ SIRT2 Q8IXJ6 2/20 0.37
▸ ACACB O00763 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8083617 0.96 MAPK1 (0.48) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL10376998 0.95 MAPK1 (0.47) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8084092 0.95 MAPK1 (0.47) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8083828 0.93 MAPK1 (0.51) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8410429 0.91 MAPK1 (0.49) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL12646434 0.89 MAPK1 (0.50) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8930354 0.89 MAPK1 (0.50) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8616165 0.88 MAPK1 (0.49) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL9588579 0.88 ACACB (0.46) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL7131378 0.88 MAPK1 (0.53) MAPK1NPSR1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-60035731-A — — None — — JP disclosed
JP-59059656-A — — None — — JP disclosed
US-6887656-B2 Color photographic element containing improved heterocyclic speed enhancing compound EASTMAN KODAK COMPANY (US) 2005-05-03 — — US disclosed
US-20040142289-A1 COLOR PHOTOGRAPHIC ELEMENT CONTAINING IMPROVED HETEROCYCLIC SPEED ENHANCING COMPOUND EASTMAN KODAK COMPANY 2004-07-22 — — US disclosed
EP-1439416-A1 Color photographic element containing improved heterocyclic speed enhancing compound EASTMAN KODAK COMPANY (US) 2004-07-21 — — EP disclosed
US-6613943-B2 Intermediates for 4-substituted-2,5-diaminophenol derivatives as phenolic cyan couplers for color photography; deblocking the 2-acyl group by hydrolysis EASTMAN KODAK COMPANY 2003-09-02 — — US disclosed
US-20030109753-A1 4-acylamino-2-hydroxy-5-substituted-acylanilide compounds and method of using them EASTMAN KODAK COMPANY 2003-06-12 — — US disclosed
EP-1316550-A1 6-Acylamino-5-substituted-benzoxazol-2-one compounds and method for using them EASTMAN KODAK COMPANY (US) 2003-06-04 — — EP disclosed
US-6525219-B1 Chemical intermediates for cyan dye forming couplers; deblocking, hydrolysis, acylation EASTMAN KODAK COMPANY 2003-02-25 — — US disclosed
US-6515176-B1 Disclosed is a 6-acylamino-5-substituted-benzoxazol-2-one compound having the structural formula I: Also disclosed is a method for forming a cyan dye-forming coupler from the above compound. The method and intermediate with a simplified EASTMAN KODAK COMPANY 2003-02-04 — — US disclosed
EP-0105991-A1 Silver halide photosensitive materials for color photography KONICA CORPORATION (JP) 1984-04-25 — — EP disclosed
JP-S5959656-A PHENOLIC COMPOUND KONISHIROKU PHOTO IND CO LTD 1984-04-05 — — JP disclosed
EP-0028099-B1 PHOTOGRAPHIC COUPLERS, EMULSIONS, MATERIALS AND PROCESSES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-11-23 — — EP disclosed
EP-0089834-A2 Light-sensitive silver halide color photographic material KONICA CORPORATION (JP) 1983-09-28 — — EP disclosed
EP-0073145-A1 A phenol cyan coupler for silver halide color photographic material KONICA CORPORATION (JP) 1983-03-02 — — EP disclosed
EP-0067689-A1 Cyan couplers and colour photographic materials containing them KONICA CORPORATION (JP) 1982-12-22 — — EP disclosed
US-4342825-A 2-BENZAMIDO PHENOLS HAVING ONE OR MORE SUBSTITUENTS SELECTED FROM FLUOROALKYLOXY, FLUOROAKYL THIO AND FLUOROALKYL SULFONYL AGFA-GEVAERT N.V. (BE) 1982-08-03 — — US disclosed
US-4333999-A PHOTOGRAPHY, SILVER HALIDE EMULSIONS EASTMAN KODAK COMPANY (US) 1982-06-08 — — US disclosed
EP-0037602-A1 Photographic elements containing novel cyan-forming colour couplers AGFA-GEVAERT N.V. (BE) 1981-10-14 — — EP disclosed
EP-0028099-A1 Photographic couplers, emulsions, materials and processes EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1981-05-06 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030109753-A1 4-acylamino-2-hydroxy-5-substituted-acylanilide compounds and method of using them CBR3, AADAC, HAAO MAPK1 4592/4885NPSR1 405/4885SMN1; SMN2 4411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.