SCHEMBL8083828

SCHEMBL8083828

CCCC(Oc1ccc(C(C)(C)CC)cc1C(C)(C)CC)C(=O)Cl

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 6/20 0.51
NPSR1 Q6W5P4 5/20 0.51
SMN1; SMN2 Q16637 5/20 0.51
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
ALDH1A1 P00352 1/20 0.51
MAPT P10636 4/20 0.40
HTT P42858 3/20 0.40
UBE2N P61088 2/20 0.40
GLA P06280 1/20 0.40
MITF O75030 1/20 0.40
SIRT2 Q8IXJ6 2/20 0.38
ACACB O00763 1/20 0.38
RAB9A P51151 3/20 0.36
RAD52 P43351 2/20 0.36
STAT3 P40763 1/20 0.36
RCE1 Q9Y256 1/20 0.36
APAF1 O14727 1/20 0.36
HSP90AA1 P07900 1/20 0.36
NOD2 Q9HC29 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6313496 0.93 MAPK1 (0.49) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8083617 0.92 MAPK1 (0.48) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL10376998 0.91 MAPK1 (0.47) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8084092 0.91 MAPK1 (0.47) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL9322305 0.90 MAPK1 (0.51) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL7131378 0.90 MAPK1 (0.53) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL12646310 0.89 MAPK1 (0.52) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL12220654 0.86 MAPK1 (0.50) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL12588861 0.84 MAPK1 (0.48) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8410429 0.83 MAPK1 (0.49) MAPK1NPSR1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0608896-B2 Process for producing aromatic amide compounds useful as cyan coupler for color photographs SUMITOMO CHEMICAL CO (JP) 2000-11-02 EP disclosed
US-5442114-A Process for producing aromatic amide compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-08-15 US disclosed
EP-0608896-A1 Process for producing aromatic amide compounds useful as cyan coupler for color photographes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-08-03 EP disclosed