SCHEMBL8410429

SCHEMBL8410429

CCCCC(Oc1ccc(C(C)(C)CC)cc1C(C)(C)CC)C([NH])=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 6/20 0.49
NPSR1 Q6W5P4 6/20 0.49
SMN1; SMN2 Q16637 5/20 0.49
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
ALDH1A1 P00352 1/20 0.49
MAPT P10636 4/20 0.41
HTT P42858 3/20 0.41
UBE2N P61088 2/20 0.41
GLA P06280 1/20 0.41
MITF O75030 1/20 0.41
RAB9A P51151 3/20 0.40
RAD52 P43351 2/20 0.40
APAF1 O14727 1/20 0.40
HSP90AA1 P07900 1/20 0.40
NOD2 Q9HC29 1/20 0.40
STAT3 P40763 1/20 0.38
RCE1 Q9Y256 1/20 0.38
SIRT2 Q8IXJ6 2/20 0.35
ACACB O00763 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6088428 0.95 MAPK1 (0.47) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL9394173 0.95 MAPK1 (0.47) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL9322305 0.93 MAPK1 (0.51) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL6313496 0.91 MAPK1 (0.49) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8930354 0.89 MAPK1 (0.50) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL12646434 0.89 MAPK1 (0.50) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8616165 0.88 MAPK1 (0.49) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL75843 0.88 MAPK1 (0.53) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8468814 0.87 NPSR1 (0.48) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8467683 0.87 MAPK1 (0.51) MAPK1NPSR1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0718277-B1 Method for producing 5-substituted-2-acylaminophenols, and 5-alkyl-2-acylaminophenol compound and N-acyl-N-(4-alkyl-phenyl)hydroxylamine compound FUJI PHOTO FILM CO LTD (JP) 1999-07-21 EP disclosed
EP-0464612-B1 Silver halide photographic materials FUJI PHOTO FILM CO LTD (JP) 1998-05-13 EP disclosed
EP-0456181-B1 Silver halide color photographic material and method for processing the same FUJI PHOTO FILM CO LTD (JP) 1996-08-14 EP disclosed
EP-0718277-A1 Method for producing 5-substituted-2-acylaminophenols, and 5-alkyl-2-acylaminophenol compound and N-acyl-N-(4-alkyl-phenyl)hydroxylamine compound FUJI PHOTO FILM CO., LTD. (JP) 1996-06-26 EP disclosed
US-5529894-A PYRAZOLOAZOLE BASED MAGENTA COUPLER, TIMING COUPLER; SHARPNESS, DESILVERING PROPERTIES FUJI PHOTO FILM CO., LTD. (JP) 1996-06-25 US disclosed
US-5500334-A Silver halide color photographic material containing pyrazole-substituted couplers FUJI PHOTO FILM CO., LTD. (JP) 1996-03-19 US disclosed
EP-0326160-B1 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1995-12-27 EP disclosed
US-5459022-A Having improved color reproducibility, rapid processability FUJI PHOTO FILM CO., LTD. (JP) 1995-10-17 US disclosed
EP-0310125-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1995-04-19 EP disclosed
EP-0423727-B1 Silver halide color photographic material containing colored coupler FUJI PHOTO FILM CO LTD (JP) 1995-01-11 EP disclosed
US-4772543-A CYAN COUPLERS KONISHIROKU PHOTO INDUSTRY, CO., LTD. (JP) 1988-09-20 US disclosed
EP-0281118-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1988-09-07 EP disclosed
US-4681837-A IMPROVED COLOR REPRODUCTIBILITY FUJI PHOTO FILM CO., LTD. (JP) 1987-07-21 US disclosed
EP-0067689-B1 CYAN COUPLERS AND COLOUR PHOTOGRAPHIC MATERIALS CONTAINING THEM KONICA CORPORATION (JP) 1986-09-10 EP disclosed
US-4554244-A PHENOL TYPE CYAN COUPLER WITH UREA GROUP KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-11-19 US disclosed
EP-0148536-A2 Silver halide photosensitive materials for color photography KONICA CORPORATION (JP) 1985-07-17 EP disclosed
US-4465766-A Silver halide photosensitive materials for color photography KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-08-14 US disclosed
US-4451559-A 2-(SUBSTITUTED PHENYL-UREIDO) PHENOL-TYPE CYAN COUPLER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-05-29 US disclosed
EP-0105991-A1 Silver halide photosensitive materials for color photography KONICA CORPORATION (JP) 1984-04-25 EP disclosed
EP-0067689-A1 Cyan couplers and colour photographic materials containing them KONICA CORPORATION (JP) 1982-12-22 EP disclosed