Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | ACHE | P22303 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6312819 | 1.00 | SMN1; SMN2 (0.57) | SMN1; SMN2PARP1POLBACHEMEN1 | |
| SCHEMBL6318848 | 0.83 | TPMT (0.48) | SMN1; SMN2PARP1POLBACHEMEN1 | |
| SCHEMBL16955311 | 0.78 | PARP1 (0.56) | SMN1; SMN2PARP1POLBACHEMEN1 | |
| SCHEMBL12802229 | 0.77 | SMN1; SMN2 (0.53) | SMN1; SMN2PARP1POLBACHEMEN1 | |
| SCHEMBL31529061 | 0.77 | CES2 (0.65) | SMN1; SMN2PARP1POLBMEN1KMT2A | |
| SCHEMBL81347 | 0.77 | ATM (0.71) | SMN1; SMN2PARP1POLBMEN1KMT2A | |
| SCHEMBL29658753 | 0.77 | ATM (0.71) | SMN1; SMN2PARP1POLBMEN1KMT2A | |
| SCHEMBL19662378 | 0.77 | SMN1; SMN2 (0.53) | SMN1; SMN2PARP1POLBACHEMEN1 | |
| SCHEMBL22010742 | 0.77 | SMN1; SMN2 (0.53) | SMN1; SMN2PARP1POLBACHEMEN1 | |
| SCHEMBL3753584 | 0.77 | CES2 (0.65) | SMN1; SMN2PARP1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6924301-B1 | Composition for treating or preventing arrhythmia | SHIONOGI & CO., LTD. (JP) | 2005-08-02 | — | — | US | disclosed |
| EP-1240906-A1 | PREVENTIVES OR REMEDIES FOR ARRHYTHMIA | SHIONOGI & CO., LTD. (JP) | 2002-09-18 | — | — | EP | disclosed |