Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9554861 | 0.91 | L3MBTL1 (0.51) | L3MBTL1SMN1; SMN2ALDH1A1MMP8KMT2A | |
| SCHEMBL15261579 | 0.85 | L3MBTL1 (0.47) | L3MBTL1SMN1; SMN2ALDH1A1MMP8KMT2A | |
| SCHEMBL7901610 | 0.82 | KMT2A (0.53) | L3MBTL1SMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL1450104 | 0.81 | L3MBTL1 (0.50) | L3MBTL1SMN1; SMN2ALDH1A1MMP8KMT2A | |
| SCHEMBL4236408 | 0.79 | L3MBTL1 (0.50) | L3MBTL1SMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL985943 | 0.79 | KMT2A (0.56) | L3MBTL1SMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL11025994 | 0.78 | L3MBTL1 (0.49) | L3MBTL1SMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL17017513 | 0.78 | L3MBTL1 (0.49) | L3MBTL1SMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL11028630 | 0.78 | L3MBTL1 (0.56) | L3MBTL1SMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL10708793 | 0.77 | L3MBTL1 (0.48) | L3MBTL1SMN1; SMN2ALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113397-A1 | Imidazo[1,2-a]pyridine derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-05-26 | — | — | US | disclosed |
| EP-1479681-A1 | IMIDAZO(1,2-a)PYRIDINE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-11-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113397-A1 | Imidazo[1,2-a]pyridine derivative | MANBA, MAN2B1, ERG28 | L3MBTL1 3913/4885SMN1; SMN2 2642/4885ALDH1A1 2550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.