Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6317891 | 0.87 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4EHSD17B10LMNA | |
| SCHEMBL6315474 | 0.79 | KDM4E (0.53) | ALDH1A1MAPTKDM4EHSD17B10LMNA | |
| SCHEMBL6314656 | 0.79 | KDM4E (0.45) | ALDH1A1MAPTKDM4EHSD17B10LMNA | |
| SCHEMBL5440337 | 0.79 | KDM4E (0.53) | ALDH1A1MAPTKDM4EHSD17B10LMNA | |
| SCHEMBL5445042 | 0.78 | KDM4E (0.56) | ALDH1A1MAPTKDM4EHSD17B10LMNA | |
| SCHEMBL6316300 | 0.78 | KDM4E (0.44) | ALDH1A1MAPTKDM4EHSD17B10LMNA | |
| SCHEMBL6315801 | 0.77 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4EHSD17B10LMNA | |
| SCHEMBL5439523 | 0.77 | KDM4E (0.58) | ALDH1A1MAPTKDM4EHSD17B10LMNA | |
| SCHEMBL5440119 | 0.77 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4EHSD17B10LMNA | |
| SCHEMBL6316569 | 0.77 | TNF (0.47) | ALDH1A1MAPTKDM4EHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6946465-B2 | Immunosuppressive effects of pteridine derivatives | 4 AZA BIOSCIENCE NV (BE) | 2005-09-20 | — | — | US | disclosed |
| US-20030236255-A1 | Immunosuppressive effects of pteridine derivatives | 4 AZA BIOSCIENCE NV (BE) | 2003-12-25 | — | — | US | disclosed |
| EP-1187615-A2 | IMMUNOSURPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES | K.U. Leuven Research & Development (BE) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000045800-A2 | IMMUNOSURPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2000-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236255-A1 | Immunosuppressive effects of pteridine derivatives | TPMT, FKBP5, RRP15 | ALDH1A1 1744/4885MAPT 388/4885KDM4E 1278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.