SCHEMBL6315378

SCHEMBL6315378

N=C(N)NCCC[C@H](N)C(=O)NN

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 2/20 0.46
NPY4R P50391 9/20 0.41
NPY1R P25929 5/20 0.41
NPY2R P49146 4/20 0.41
NPY5R Q15761 4/20 0.41
GNAI3 P08754 1/20 0.41
GNAO1 P09471 1/20 0.41
GNAI1 P63096 1/20 0.41
RRM1 P23921 1/20 0.39
OTC P00480 1/20 0.38
ALOX15 P16050 1/20 0.38
MEN1 O00255 1/20 0.37
CYP1A2 P05177 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
DDAH1 O94760 1/20 0.36
NOS1 P29475 1/20 0.36
SLC15A1 P46059 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28608119 1.00 DPP7 (0.46) DPP7NPY4RNPY1RNPY2RNPY5R
SCHEMBL23610947 0.87 DPP7 (0.61) DPP7NPY4RNPY1RNPY2RNPY5R
SCHEMBL23626315 0.87 DPP7 (0.61) DPP7NPY4RNPY1RNPY2RNPY5R
SCHEMBL4104140 0.86 DPP7 (0.46) DPP7NPY4RNPY1RNPY2RNPY5R
SCHEMBL197663 0.86 DPP7 (0.46) DPP7NPY4RNPY1RNPY2RNPY5R
SCHEMBL6868746 0.86 DPP7 (0.46) DPP7NPY4RNPY1RNPY2RNPY5R
SCHEMBL7326934 0.84 DPP7 (0.49) DPP7NPY4RNPY1RNPY2RNPY5R
Hydrochloric Acid SCHEMBL2132822 0.84 DPP7 (0.45) DPP7NPY4RNPY1RNPY2RNPY5R
SCHEMBL1388277 0.84 DPP7 (0.49) DPP7NPY4RNPY1RNPY2RNPY5R
SCHEMBL15165702 0.84 DPP7 (0.49) DPP7NPY4RNPY1RNPY2RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6958325-B2 Cationic polysaccharide compositions EFRAT BIOPOLYMERS LIMITED (IL) 2005-10-25 US disclosed
US-20020146826-A1 Biodegradabel polysaccharide derivative for use in human therapeutic and diagnostics POLYGENE LTD. 2002-10-10 US disclosed
EP-1222926-A1 Cationic polysaccharide compositions Polygene Ltd. (IL) 2002-07-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020146826-A1 Biodegradabel polysaccharide derivative for use in human therapeutic and diagnostics ALG1, CD44, CHIT1 DPP7 708/4885NPY4R 2602/4885NPY1R 3078/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.