SCHEMBL631552

SCHEMBL631552

C=C(C)C(=O)OC(C)N(C(=O)O)C(CC)[Si](OCC)(OCC)OCC

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.34
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2911712 0.85 TSHR (0.32) TSHR
SCHEMBL631550 0.81
SCHEMBL15796950 0.77 THRB (0.35) THRB
SCHEMBL1253678 0.74 TSHR (0.41) THRBTSHR
SCHEMBL25276153 0.72 THRB (0.38) THRBTSHR
SCHEMBL138292 0.72 THRB (0.38) THRBTSHR
SCHEMBL14842537 0.72 TSHR (0.30) TSHR
SCHEMBL5071943 0.72 THRB (0.35) THRBTSHR
SCHEMBL19970538 0.71 ALDH1A1 (0.31) TSHR
Hydrogen Sulfide SCHEMBL4951624 0.71 THRB (0.37) THRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2419458-A1 PROCATALYST COMPOSITION WITH SILYL GLUTARATE AND METHOD Dow Global Technologies LLC (US) 2012-02-22 EP disclosed
EP-2315789-A1 CATALYST COMPOSITION WITH MIXED SELECTIVITY CONTROL AGENT AND POLYMERISATION METHOD USING IT Dow Global Technologies LLC (US) 2011-05-04 EP disclosed
WO-2010120973-A1 PROCATALYST COMPOSITION WITH SILYL GLUTARATE AND METHOD DOW GLOBAL TECHNOLOGIES INC. (US) 2010-10-21 WO disclosed
WO-2010021762-A1 CATALYST COMPOSITION WITH MIXED SELECTIVITY CONTROL AGENT AND POLYMERISATION METHOD USING IT DOW GLOBAL TECHNOLOGIES INC. (US) 2010-02-25 WO disclosed