Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | RAB7A | P51149 | 3/20 | 0.49 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PTPRB | P23467 | 1/20 | 0.43 |
| ▸ | PTPRE | P23469 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6206528 | 0.87 | RAB7A (0.55) | MAPTHPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6316036 | 0.85 | PTPN1 (0.47) | MAPTSMN1; SMN2ALDH1A1LMNATP53 | |
| SCHEMBL6322930 | 0.85 | PTPN1 (0.47) | MAPTSMN1; SMN2ALDH1A1LMNARAB7A | |
| SCHEMBL6315228 | 0.83 | PTPN1 (0.43) | MAPTHPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6317364 | 0.83 | LMNA (0.52) | MAPTHPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6316165 | 0.83 | PTPN1 (0.48) | MAPTSMN1; SMN2ALDH1A1LMNARAB7A | |
| SCHEMBL6314369 | 0.83 | MAPT (0.57) | MAPTHPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7159868 | 0.83 | HPGD (0.47) | MAPTHPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6207392 | 0.82 | MAPT (0.56) | MAPTLMNATP53PTPN1POLB | |
| SCHEMBL6315979 | 0.82 | MEN1 (0.54) | MAPTMEN1KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030069267-A1 | Modulators of protein tyrosine phosphatases (PTPases) | MOLLER NIELS PETER HUNDAHL (DK) | 2003-04-10 | — | — | US | claimed |
| US-6951878-B2 | Benzo[b]thiophenyl or tetrahydro-benzo[b]thiophenyl modulators of protein tyrosine phosphatases (PTPases) | NOVO NORDISK A/S (DK) | 2005-10-04 | — | — | US | disclosed |
| US-6410586-B1 | ANTICOAGULANTS; INSULIN RESISTANCE; ANTIALLERGENS | NOVO NORDISK A/S (DK) | 2002-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069267-A1 | Modulators of protein tyrosine phosphatases (PTPases) | PTPRCAP, PTPRS, PTPRA | MAPT 475/4885HPGD 2593/4885SMN1; SMN2 1576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.