Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6316247 | 0.69 | — | — | |
| SCHEMBL826964 | 0.69 | — | — | |
| SCHEMBL26482661 | 0.69 | MAOA (0.35) | MAOA | |
| SCHEMBL31326784 | 0.69 | DAO (0.35) | — | |
| SCHEMBL6345893 | 0.67 | — | — | |
| SCHEMBL5414147 | 0.64 | MAOA (0.32) | MAOA | |
| SCHEMBL4272161 | 0.64 | TAAR1 (0.37) | MAOAALDH1A1 | |
| SCHEMBL13266841 | 0.64 | TAAR1 (0.34) | MAOA | |
| SCHEMBL6316650 | 0.63 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL6287369 | 0.63 | MAOA (0.32) | MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050059657-A1 | Aminoisoxazole derivatives active as kinase inhibitors | PFIZER ITALIA S.R.L. (IT) | 2005-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059657-A1 | Aminoisoxazole derivatives active as kinase inhibitors | MAP3K9, MAP3K19, MAP4K2 | MAOA 1199/4885ALDH1A1 4444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.