SCHEMBL6316888

SCHEMBL6316888

O=C(Cl)Cl.O=C(Cl)OC(Cl)(Cl)Cl

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4986 0.97
SCHEMBL642649 0.97 ALDH1A1 (0.33) ALDH1A1TP53TSHR
Ammonia Solution, Strong SCHEMBL27315898 0.93
Hydrochloric Acid SCHEMBL3929579 0.93
SCHEMBL8837461 0.90 ALDH1A1 (0.37) ALDH1A1TP53TSHR
SCHEMBL4961406 0.88
Benzene SCHEMBL6227182 0.88 ALDH1A1 (0.35) ALDH1A1TP53TSHR
Methylene Chloride SCHEMBL28451203 0.88
Cyclohexane SCHEMBL29140114 0.88
SCHEMBL28007505 0.83 ALDH1A1 (0.32) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8445734-B2 Photolabile protective groups for improved processes to prepare oligonucleotide arrays NIGU CHEMIE GMBH (DE) 2013-05-21 US claimed
CN-113105365-A Process for preparing isocyanate by adopting phosgenation reaction 新沂市永诚化工有限公司 2021-07-13 CN disclosed
US-6858751-B1 Process for preparing aliphatic fluorofomates ISOCHEM (FR) 2005-02-22 US disclosed
US-20040097492-A1 Anti-infective agents ABBOTT LABORATORIES 2004-05-20 US disclosed
CN-1495184-A Substituted purine derivative, its preparation method, application and composition containing it �ճ�˹�عɷݹ�˾ 2004-05-12 CN disclosed
CN-1101816-C Substituted purine derivatives, their preparation, their use and compositions containing them HOECHST AG (DE) 2003-02-19 CN disclosed
CN-1364161-A N-substituted perhydrodiazines BASF AG (DE) 2002-08-14 CN disclosed
CN-1193623-A Substituted purine derivatives, their preparation, their use and compositions containing them HOECHST AG (DE) 1998-09-23 CN disclosed
WO-1997042177-A1 PROCESS FOR THE PREPARATION OF UREIDE DERIVATIVES AND NEW INTERMEDIATES OF SYNTHESIS ABRES ASSOCIATED BIOTECHNOLOGY RESEARCH S.R.L. (IT) 1997-11-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040097492-A1 Anti-infective agents POLR1C, RPL5, POLB ALDH1A1 1434/4885TP53 3666/4885TSHR 4415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.