Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 9/20 | 0.70 |
| ▸ | HTR1A | P08908 | 17/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL6311056 | 1.00 | HTR1A (0.70) | HTR1ASLC6A4 | |
| Oxalic Acid SCHEMBL6317600 | 1.00 | HTR1A (0.70) | HTR1ASLC6A4 | |
| Oxalic Acid SCHEMBL6311323 | 1.00 | HTR1A (0.70) | HTR1ASLC6A4 | |
| Oxalic Acid SCHEMBL6312730 | 0.90 | HTR1A (0.68) | HTR1ASLC6A4 | |
| Oxalic Acid SCHEMBL5762570 | 0.86 | HTR1A (0.93) | HTR1ASLC6A4 | |
| Oxalic Acid SCHEMBL5762153 | 0.86 | HTR1A (0.93) | HTR1ASLC6A4 | |
| Oxalic Acid SCHEMBL5761821 | 0.86 | HTR1A (0.93) | HTR1ASLC6A4 | |
| Oxalic Acid SCHEMBL5759524 | 0.86 | HTR1A (0.93) | HTR1ASLC6A4 | |
| Oxalic Acid SCHEMBL5761310 | 0.86 | HTR1A (0.93) | HTR1ASLC6A4 | |
| Oxalic Acid SCHEMBL5759022 | 0.86 | HTR1A (0.93) | HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6844344-B2 | Benzofuran derivatives | ELI LILLY AND COMPANY (US) | 2005-01-18 | — | — | US | disclosed |
| US-20030232833-A1 | Benzofuran derivatives | ELI LILLY AND COMPANY | 2003-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232833-A1 | Benzofuran derivatives | BRD1, BPTF, HTR1F | SLC6A4 227/4885HTR1A 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.