SCHEMBL6317573

SCHEMBL6317573

CC(C)COC(=O)C1C=CC=CC1C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.37
ALDH1A1 P00352 3/20 0.37
RAB9A P51151 3/20 0.36
HSP90AA1 P07900 1/20 0.34
HSP90AB1 P08238 1/20 0.34
CHRM2 P08172 2/20 0.34
CHRM4 P08173 2/20 0.34
CHRM5 P08912 2/20 0.34
CHRM1 P11229 2/20 0.34
CHRM3 P20309 2/20 0.34
NPC1 O15118 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CACNA1F O60840 2/20 0.33
CACNA1D Q01668 2/20 0.33
CACNA1S Q13698 2/20 0.33
CACNA1C Q13936 2/20 0.33
HTT P42858 1/20 0.32
PPARG P37231 1/20 0.31
GAPDH P04406 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6316280 0.93 TSHR (0.41) TSHRALDH1A1RAB9AHSP90AA1HSP90AB1
SCHEMBL6325169 0.76 PPM1B (0.42) TSHRALDH1A1CHRM2CHRM4CHRM5
SCHEMBL6319158 0.74 ALDH1A1 (0.42) TSHRALDH1A1TDP1L3MBTL1PPARG
SCHEMBL6316629 0.72 POLB (0.36) TSHRALDH1A1TDP1HTT
SCHEMBL6317561 0.72 RAB9A (0.38) TSHRALDH1A1RAB9AHSP90AA1HSP90AB1
SCHEMBL11579330 0.71 POLB (0.36) TDP1
SCHEMBL156544 0.71 POLB (0.36) TDP1
SCHEMBL1169269 0.70 TSHR (0.36) TSHRALDH1A1RAB9AHSP90AA1HSP90AB1
SCHEMBL28068417 0.70 RAB9A (0.42) TSHRALDH1A1RAB9AHSP90AA1HSP90AB1
SCHEMBL6316661 0.70 ALDH1A1 (0.42) TSHRALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6921830-B2 Method for purifying an organic solvent for the purposes of absorption of maleic acid anhydride BASF AKTIENGESELLSCHAFT (DE) 2005-07-26 US disclosed
US-20040127726-A1 Method for purifying an organic solvent for the purposes of absorption of maleic acid anhydride BASF AKTIENGESELLSCHAFT (DE) 2004-07-01 US disclosed