⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6322972 | 0.83 | SLC22A3 (0.37) | — | |
| SCHEMBL6319894 | 0.82 | — | — | |
| SCHEMBL6319576 | 0.79 | — | — | |
| SCHEMBL6324138 | 0.79 | — | — | |
| SCHEMBL6319582 | 0.78 | LMNA (0.31) | — | |
| SCHEMBL6268716 | 0.78 | MAPT (0.31) | — | |
| SCHEMBL6317946 | 0.77 | PDE5A (0.33) | — | |
| SCHEMBL6318624 | 0.76 | LMNA (0.30) | — | |
| SCHEMBL6325948 | 0.76 | — | — | |
| SCHEMBL6272311 | 0.74 | CYP1A2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | QUATRX PHARMACEUTICALS CO. | 2005-06-30 | — | — | US | claimed |
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | QUATRX PHARMACEUTICALS CO. | 2005-06-30 | — | — | US | disclosed |