Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.43 |
| ▸ | HTR2B | P41595 | 7/20 | 0.43 |
| ▸ | HTR2A | P28223 | 6/20 | 0.43 |
| ▸ | ITGB2 | P05107 | 4/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.43 |
| ▸ | ITGAL | P20701 | 4/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6310624 | 0.92 | ITGB2 (0.42) | HTR2CHTR2BHTR2AITGB2ICAM1 | |
| SCHEMBL6199467 | 0.83 | ITGAL (0.48) | ITGB2ICAM1ITGALPTPN11 | |
| SCHEMBL6312229 | 0.83 | ITGAL (0.49) | ITGB2ICAM1ITGAL | |
| SCHEMBL6199827 | 0.83 | ITGAL (0.45) | ITGB2ICAM1ITGALPTPN11 | |
| SCHEMBL6318688 | 0.80 | ITGAL (0.69) | HTR2CHTR2BHTR2AITGB2ICAM1 | |
| SCHEMBL6197119 | 0.80 | ITGAL (0.42) | ITGB2ICAM1ITGALPTPN11 | |
| SCHEMBL6196144 | 0.80 | ITGAL (0.46) | ITGB2ICAM1ITGAL | |
| SCHEMBL6199010 | 0.79 | ITGAL (0.64) | ITGB2ICAM1ITGAL | |
| SCHEMBL6308779 | 0.78 | ITGAL (0.49) | ITGB2ICAM1ITGAL | |
| SCHEMBL6410178 | 0.76 | MEN1 (0.49) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867203-B2 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-03-15 | — | — | US | disclosed |
| US-20040116518-A1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES | 2004-06-17 | — | — | US | disclosed |