Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.46 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.45 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.45 |
| ▸ | ITGAL | P20701 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6312229 | 0.84 | ITGAL (0.49) | KMT2AALDH1A1HPGDITGB2ICAM1 | |
| SCHEMBL6196144 | 0.82 | ITGAL (0.46) | MEN1KMT2AALDH1A1ITGB2ICAM1 | |
| SCHEMBL6199467 | 0.82 | ITGAL (0.48) | ITGB2ICAM1ITGAL | |
| SCHEMBL6199010 | 0.80 | ITGAL (0.64) | MEN1KMT2AITGB2ICAM1ITGAL | |
| SCHEMBL6410181 | 0.80 | ITGAL (0.73) | MEN1KMT2AALDH1A1ABL1RIN1 | |
| SCHEMBL6199827 | 0.78 | ITGAL (0.45) | ITGB2ICAM1ITGALSMN1; SMN2 | |
| SCHEMBL6308779 | 0.78 | ITGAL (0.49) | MEN1KMT2AALDH1A1ITGB2ICAM1 | |
| SCHEMBL6318679 | 0.76 | HTR2C (0.43) | ITGB2ICAM1ITGAL | |
| SCHEMBL6197119 | 0.76 | ITGAL (0.42) | KMT2AALDH1A1ITGB2ICAM1ITGAL | |
| SCHEMBL6199566 | 0.74 | ITGAL (0.51) | ALDH1A1ITGB2ICAM1ITGALTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050250768-A1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES | 2005-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250768-A1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ICAM1, VCAM1, EPCAM | MEN1 2594/4885KMT2A 4094/4885ALDH1A1 484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.