Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 16/20 | 0.64 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2605261 | 0.88 | SLC6A9 (0.74) | SLC6A9TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL2605383 | 0.88 | SLC6A9 (0.64) | SLC6A9GPR139TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL631885 | 0.84 | SLC6A9 (0.59) | SLC6A9BRD4CREBBP | |
| SCHEMBL2605382 | 0.84 | SLC6A9 (0.62) | SLC6A9 | |
| SCHEMBL2605184 | 0.78 | SLC6A9 (1.00) | SLC6A9 | |
| SCHEMBL2605303 | 0.78 | SLC6A9 (1.00) | SLC6A9 | |
| SCHEMBL2123535 | 0.77 | SLC6A9 (0.73) | SLC6A9CYP2C9 | |
| SCHEMBL2605270 | 0.76 | SLC6A9 (0.64) | SLC6A9 | |
| SCHEMBL2605256 | 0.75 | SLC6A9 (0.67) | SLC6A9CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4174502 | 0.74 | SLC6A9 (0.76) | SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419431-A1 | DERIVATIVES OF N-[(7-AZA-BICYCLO[2.2.1]HEPT-1-YL)-ARYL-METHYL]-BENZAMIDE, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-02-22 | — | — | EP | claimed |
| WO-2010119222-A1 | DERIVATIVES OF N-[(7-AZA-BICYCLO[2.2.1]HEPT-1-YL)-ARYL-METHYL]-BENZAMIDE, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-10-21 | — | — | WO | claimed |
| EP-2419431-A1 | DERIVATIVES OF N-[(7-AZA-BICYCLO[2.2.1]HEPT-1-YL)-ARYL-METHYL]-BENZAMIDE, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-02-22 | — | — | EP | disclosed |
| WO-2010119222-A1 | DERIVATIVES OF N-[(7-AZA-BICYCLO[2.2.1]HEPT-1-YL)-ARYL-METHYL]-BENZAMIDE, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-10-21 | — | — | WO | disclosed |