Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 17/20 | 0.59 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL631883 | 0.84 | SLC6A9 (0.64) | SLC6A9CREBBPBRD4 | |
| SCHEMBL2605383 | 0.81 | SLC6A9 (0.64) | SLC6A9 | |
| SCHEMBL2605261 | 0.79 | SLC6A9 (0.74) | SLC6A9SLC6A5 | |
| SCHEMBL2123535 | 0.78 | SLC6A9 (0.73) | SLC6A9SLC6A5 | |
| SCHEMBL2605382 | 0.76 | SLC6A9 (0.62) | SLC6A9 | |
| SCHEMBL2605184 | 0.74 | SLC6A9 (1.00) | SLC6A9SLC6A5 | |
| SCHEMBL2605303 | 0.74 | SLC6A9 (1.00) | SLC6A9SLC6A5 | |
| SCHEMBL2605270 | 0.74 | SLC6A9 (0.64) | SLC6A9 | |
| SCHEMBL2605256 | 0.74 | SLC6A9 (0.67) | SLC6A9SLC6A5 | |
| SCHEMBL2605269 | 0.72 | SLC6A9 (0.61) | SLC6A9SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419431-A1 | DERIVATIVES OF N-[(7-AZA-BICYCLO[2.2.1]HEPT-1-YL)-ARYL-METHYL]-BENZAMIDE, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-02-22 | — | — | EP | claimed |
| WO-2010119222-A1 | DERIVATIVES OF N-[(7-AZA-BICYCLO[2.2.1]HEPT-1-YL)-ARYL-METHYL]-BENZAMIDE, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-10-21 | — | — | WO | claimed |
| EP-2419431-A1 | DERIVATIVES OF N-[(7-AZA-BICYCLO[2.2.1]HEPT-1-YL)-ARYL-METHYL]-BENZAMIDE, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-02-22 | — | — | EP | disclosed |
| WO-2010119222-A1 | DERIVATIVES OF N-[(7-AZA-BICYCLO[2.2.1]HEPT-1-YL)-ARYL-METHYL]-BENZAMIDE, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-10-21 | — | — | WO | disclosed |