Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.57 |
| ▸ | BCR | P11274 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28805236 | 0.94 | ABL1 (0.56) | ABL1ABCB1BCRMAPTNPC1 | |
| SCHEMBL28521639 | 0.94 | ABL1 (0.56) | ABL1ABCB1BCRMAPTNPC1 | |
| SCHEMBL3491387 | 0.90 | ABL1 (0.52) | ABL1ABCB1BCRMAPTNPC1 | |
| SCHEMBL27938882 | 0.88 | ABL1 (0.50) | ABL1ABCB1BCRMAPTNPC1 | |
| Propanol SCHEMBL27573292 | 0.85 | BACE1 (0.50) | ABL1ABCB1BCRMAPTNPC1 | |
| SCHEMBL28714568 | 0.83 | BACE1 (0.56) | ABL1ABCB1BCRMAPTNPC1 | |
| SCHEMBL29012812 | 0.82 | ALDH1A1 (0.49) | ABL1ABCB1BCRMAPTNPC1 | |
| SCHEMBL7689092 | 0.82 | POLB (0.49) | ABL1ABCB1BCRMAPTNPC1 | |
| SCHEMBL12715050 | 0.81 | ABL1 (0.79) | ABL1ABCB1BCRMAPTNPC1 | |
| SCHEMBL27043229 | 0.81 | TDP1 (0.67) | ABL1ABCB1BCRMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916893-B2 | Polymerization-active transition metal complexes having bulky ligand systems | SER. V. GMBH (DE) | 2005-07-12 | — | — | US | disclosed |
| US-20040171774-A1 | Polymerization-active transition metal complexes having bulky ligand systems | RIEGER BERNHARD (DE) | 2004-09-02 | — | — | US | disclosed |
| EP-1242434-B1 | POLYMERIZATION-ACTIVE TRANSITION METAL COMPLEX COMPOUNDS COMPRISING A STERICALLY DEMANDING LIGAND SYSTEM | SER V GMBH (DE) | 2004-06-02 | — | — | EP | disclosed |
| EP-1398330-A2 | Transition metal complexes having a bulky ligand system used in polymerisation | Ser.V. GmbH (DE) | 2004-03-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171774-A1 | Polymerization-active transition metal complexes having bulky ligand systems | AP1M1, CCNC, CLTB | ABL1 509/4885ABCB1 3362/4885BCR 1021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.