Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | BCR | P11274 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6951995 | 0.83 | ESR2 (0.59) | POLBGAAABL1ABCB1BCR | |
| SCHEMBL6319062 | 0.82 | ABL1 (0.57) | ABL1ABCB1BCRKMT2AALDH1A1 | |
| SCHEMBL9685314 | 0.81 | ESR2 (0.44) | GAAADORA1ADORA2AMEN1KMT2A | |
| SCHEMBL27930441 | 0.81 | ESR2 (0.47) | ALDH1A1KDM4EARMAPTLMNA | |
| SCHEMBL140629 | 0.79 | PGR (0.49) | POLBGAAADORA1ADORA2AMEN1 | |
| SCHEMBL27693511 | 0.79 | ESR2 (0.48) | POLBGAAADORA1ADORA2AMEN1 | |
| SCHEMBL28805236 | 0.78 | ABL1 (0.56) | ADORA1ABL1ABCB1BCRADORA2A | |
| SCHEMBL3491387 | 0.78 | ABL1 (0.52) | GAAABL1ABCB1BCRMEN1 | |
| SCHEMBL28521639 | 0.78 | ABL1 (0.56) | ABL1ABCB1BCRKMT2AALDH1A1 | |
| SCHEMBL27938882 | 0.76 | ABL1 (0.50) | ABL1ABCB1BCRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002018364-A2 | PROCESS FOR PREPARING 2-PHENYL-3-AMINOBENZOTHIOPHENES | ELI LILLY AND COMPANY (US) | 2002-03-07 | — | — | WO | disclosed |