Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632134 | 0.84 | LMNA (0.53) | LMNAL3MBTL1TDP1ALDH1A1PKM | |
| SCHEMBL22207807 | 0.81 | ALDH1A1 (0.46) | LMNAL3MBTL1TDP1ALDH1A1PKM | |
| SCHEMBL18825262 | 0.77 | LMNA (0.65) | LMNACES2CES1L3MBTL1TDP1 | |
| SCHEMBL31020337 | 0.75 | LMNA (0.50) | LMNACES2CES1L3MBTL1TDP1 | |
| SCHEMBL9366693 | 0.72 | GAA (0.70) | LMNACES2CES1L3MBTL1ALDH1A1 | |
| SCHEMBL8852715 | 0.72 | KMT2A (0.42) | LMNACES2CES1L3MBTL1TDP1 | |
| SCHEMBL5425626 | 0.72 | BCHE (0.53) | LMNACES2CES1L3MBTL1TDP1 | |
| SCHEMBL15581083 | 0.72 | ALDH1A1 (0.47) | LMNACES2CES1ALDH1A1PKM | |
| SCHEMBL22207855 | 0.71 | TRPV1 (0.73) | LMNAALDH1A1PKMTRPV1HTT | |
| SCHEMBL5430264 | 0.71 | LMNA (0.46) | LMNACES2CES1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |