Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942785 | 0.96 | TSHR (0.47) | TSHRTDP1ALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL3349311 | 0.92 | TSHR (0.42) | TSHRTDP1ALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL2689920 | 0.92 | TSHR (0.50) | TSHRTDP1ALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL16651566 | 0.92 | TSHR (0.50) | TSHRTDP1ALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL1228085 | 0.91 | ALDH1A1 (0.43) | TDP1ALDH1A1L3MBTL1MAPK1HTT | |
| SCHEMBL2946643 | 0.90 | ALDH1A1 (0.37) | TDP1ALDH1A1L3MBTL1MAPK1POLB | |
| SCHEMBL2097594 | 0.88 | ALDH1A1 (0.43) | TDP1ALDH1A1L3MBTL1MAPK1HTT | |
| SCHEMBL10599434 | 0.87 | TSHR (0.56) | TSHRTDP1ALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL2223012 | 0.87 | TSHR (0.48) | TSHRTDP1ALDH1A1POLBAPEX1 | |
| SCHEMBL3268510 | 0.87 | POLB (0.39) | TSHRTDP1ALDH1A1L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887281-B2 | N-heteroarylmethyl-p-phenylenediamine derivatives as well as oxidation dyeing agents containing these compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2005-05-03 | — | — | US | claimed |
| US-20050015898-A1 | N-heteroarylmethyl-p-phenylenediamine derivatives as well as oxidation dyeing agents containing these compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2005-01-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050015898-A1 | N-heteroarylmethyl-p-phenylenediamine derivatives as well as oxidation dyeing agents containing these compounds | TYR, PNMT, DDT | TSHR 3830/4885TDP1 2562/4885ALDH1A1 66/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.