Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | ITGAL | P20701 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 2/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7592861 | 0.87 | NPC1 (0.37) | RAB9ANPC1HPGDNPSR1SMN1; SMN2 | |
| SCHEMBL6321843 | 0.84 | NPC1 (0.38) | RAB9ANPC1HPGDNPSR1KDM4E | |
| SCHEMBL6319700 | 0.80 | NPC1 (0.35) | RAB9ANPC1HPGDKDM4EMEN1 | |
| SCHEMBL4847287 | 0.77 | SMN1; SMN2 (0.33) | RAB9ANPC1NPSR1KDM4EMEN1 | |
| SCHEMBL4846541 | 0.77 | SMN1; SMN2 (0.35) | RAB9ANPC1NPSR1KDM4EMEN1 | |
| SCHEMBL6321851 | 0.76 | KDM4E (0.36) | RAB9ANPC1ITGB2ICAM1ITGAL | |
| SCHEMBL13681624 | 0.75 | GRM5 (0.38) | NPSR1KDM4EHTTALDH1A1MAPT | |
| SCHEMBL7164438 | 0.74 | NPSR1 (0.39) | RAB9ANPC1ITGB2ICAM1ITGAL | |
| SCHEMBL6329470 | 0.73 | CTNNB1 (0.35) | NPSR1MEN1KMT2AHTTALDH1A1 | |
| SCHEMBL7593128 | 0.72 | NPC1 (0.35) | RAB9ANPC1HPGDNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6878665-B2 | Diphosphines, their complexes with transisition metals and their use in asymmetric synthesis | SYNKEM (FR) | 2005-04-12 | — | — | US | disclosed |
| US-20040260101-A1 | Novel diphosphines, their complexes with transisition metals and their use in asymmetric synthesis | SYNKEM (FR) | 2004-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040260101-A1 | Novel diphosphines, their complexes with transisition metals and their use in asymmetric synthesis | TPI1, TCP1, TTI2 | RAB9A 119/4885NPC1 1888/4885ITGB2 1336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.