Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | DCAF1 | Q9Y4B6 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4883244 | 0.88 | SMN1; SMN2 (0.56) | SMN1; SMN2MEN1KMT2APKMHPGD | |
| SCHEMBL4883253 | 0.88 | SMN1; SMN2 (0.56) | SMN1; SMN2MEN1KMT2APKMHPGD | |
| SCHEMBL4889231 | 0.88 | SMN1; SMN2 (0.56) | SMN1; SMN2MEN1KMT2APKMHPGD | |
| SCHEMBL4848178 | 0.84 | PKM (0.54) | SMN1; SMN2MEN1KMT2APKMHPGD | |
| SCHEMBL4857951 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2APKM | |
| SCHEMBL4890080 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2APKM | |
| SCHEMBL4849427 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2APKM | |
| SCHEMBL4855845 | 0.79 | PKM (0.48) | SMN1; SMN2MEN1KMT2APKM | |
| SCHEMBL8092732 | 0.79 | SMN1; SMN2 (0.63) | SMN1; SMN2MEN1KMT2APKMLMNA | |
| SCHEMBL5272038 | 0.77 | SMN1; SMN2 (0.61) | SMN1; SMN2MEN1KMT2APKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6914160-B1 | Oxytocin inhibitors | PFIZER INC (US) | 2005-07-05 | — | — | US | disclosed |