Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | BACE1 | P56817 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2087231 | 0.81 | MAOB (0.64) | MAOBGSK3BBACE1MEN1KMT2A | |
| SCHEMBL3914637 | 0.78 | FFAR1 (0.44) | MAOBFFAR1 | |
| SCHEMBL3906109 | 0.76 | CYP4F2 (0.53) | MAOBGSK3BBACE1MEN1KMT2A | |
| SCHEMBL8754509 | 0.73 | MAPK1 (0.52) | MEN1KMT2APOLBTDP1 | |
| SCHEMBL6328433 | 0.72 | ALDH1A1 (0.45) | MAOBMEN1KMT2APOLBMME | |
| SCHEMBL6327588 | 0.72 | ALDH1A1 (0.45) | MAOBMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL5096512 | 0.72 | MAOB (0.57) | MAOBGSK3BBACE1FFAR1MME | |
| SCHEMBL2087094 | 0.72 | MMP1 (0.56) | MAOBGSK3BBACE1FFAR1MEN1 | |
| SCHEMBL2087082 | 0.71 | MAOB (1.00) | MAOBGSK3BBACE1MMP1PPARA | |
| SCHEMBL3720430 | 0.70 | MAOB (0.50) | MAOBGSK3BBACE1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6858602-B2 | Compounds for the treatment of metabolic disorders | WELLSTAT THERAPEUTICS CORPORATION (US) | 2005-02-22 | — | — | US | disclosed |