Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 7/20 | 0.59 |
| ▸ | ADRA2B | P18089 | 7/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 7/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.59 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | BLM | P54132 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | DRD1 | P21728 | 2/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26672809 | 0.85 | ADRA2A (0.70) | ADRA2AADRA2BADRA2CADRB1ADRB3 | |
| SCHEMBL23484536 | 0.78 | KDM4E (0.67) | ADRA2AADRA2BADRA2CADRB1ADRB3 | |
| SCHEMBL28196899 | 0.74 | ADRA2A (0.60) | ADRA2AADRA2BADRA2CADRB1ADRB3 | |
| SCHEMBL28196898 | 0.74 | ADRA2A (0.60) | ADRA2AADRA2BADRA2CADRB1ADRB3 | |
| SCHEMBL2294173 | 0.73 | KDM4E (0.68) | ADRA2AADRA2BADRA2CADRB1ADRB3 | |
| SCHEMBL2299016 | 0.73 | KDM4E (0.68) | ADRA2AADRA2BADRA2CADRB1ADRB3 | |
| SCHEMBL3443558 | 0.73 | KDM4E (0.68) | ADRA2AADRA2BADRA2CADRB1ADRB3 | |
| SCHEMBL5492653 | 0.73 | ADRA2A (0.47) | ADRA2AADRA2BADRA2CADRB1ADRB3 | |
| SCHEMBL2458054 | 0.72 | ADRB2 (0.50) | ADRA2AADRA2BADRA2CADRB1ADRB3 | |
| SCHEMBL7153230 | 0.72 | ADRB2 (0.50) | ADRA2AADRA2BADRA2CADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6852731-B2 | Antiviral compounds | PFIZER (US) | 2005-02-08 | — | — | US | claimed |
| US-20040242884-A1 | ANTIVIRAL COMPOUNDS | PHARMACIA & UPJOHN COMPANY | 2004-12-02 | — | — | US | claimed |
| EP-1472260-A2 | THIENO(3,2-B)PYRIDONES AS ANTIVIRAL COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 2004-11-03 | — | — | EP | claimed |
| WO-2003059878-A2 | THIENO (3, 2-B) PYRIDONES AS ANTIVIRAL COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 2003-07-24 | — | — | WO | claimed |
| US-6852731-B2 | Antiviral compounds | PFIZER (US) | 2005-02-08 | — | — | US | disclosed |
| US-20040242884-A1 | ANTIVIRAL COMPOUNDS | PHARMACIA & UPJOHN COMPANY | 2004-12-02 | — | — | US | disclosed |
| EP-1472260-A2 | THIENO(3,2-B)PYRIDONES AS ANTIVIRAL COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003059878-A2 | THIENO (3, 2-B) PYRIDONES AS ANTIVIRAL COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 2003-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242884-A1 | ANTIVIRAL COMPOUNDS | ZC3HAV1, IRF3, IFNAR1 | ADRA2A 3916/4885ADRA2B 4154/4885ADRA2C 3124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.