Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10563916 | 0.85 | F2 (0.39) | KDM4EGRM5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4155842 | 0.80 | GRM5 (0.38) | KDM4EGRM5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6323498 | 0.78 | ASIC3 (0.35) | KDM4EGRM5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6861227 | 0.77 | GRM5 (0.42) | KDM4EGRM5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6323057 | 0.77 | KDM4E (0.39) | KDM4ENPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL31471018 | 0.76 | MAPK8 (0.43) | GRM5NPC1RAB9AALDH1A1GABRA5 | |
| SCHEMBL31546695 | 0.76 | GRM5 (0.35) | KDM4EGRM5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21827566 | 0.76 | MAPK8 (0.43) | GRM5NPC1RAB9AALDH1A1GABRA5 | |
| SCHEMBL31546840 | 0.75 | GRM5 (0.35) | KDM4EGRM5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31546688 | 0.73 | SLC6A2 (0.35) | KDM4EGRM5NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030073581-A1 | Herbicidal 2-alkynyl-pyri (mi) dines | WYETH | 2003-04-17 | — | — | US | claimed |
| EP-1238586-A1 | Herbicidal 2-alkynyl-pyri(mi)dines | BASF AKTIENGESELLSCHAFT (DE) | 2002-09-11 | — | — | EP | claimed |
| US-6872690-B2 | Herbicidal 2-alkynyl-pyri (mi) dines | WYETH (US) | 2005-03-29 | — | — | US | disclosed |
| US-20030073581-A1 | Herbicidal 2-alkynyl-pyri (mi) dines | WYETH | 2003-04-17 | — | — | US | disclosed |
| EP-1238586-A1 | Herbicidal 2-alkynyl-pyri(mi)dines | BASF AKTIENGESELLSCHAFT (DE) | 2002-09-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073581-A1 | Herbicidal 2-alkynyl-pyri (mi) dines | DDT, AOX1, RIOX2 | KDM4E 852/4885GRM5 866/4885NPC1 3943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.