Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 14/20 | 0.46 |
| ▸ | CTSK | P43235 | 10/20 | 0.46 |
| ▸ | CTSB | P07858 | 5/20 | 0.44 |
| ▸ | CTSL | P07711 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6320857 | 1.00 | KCNA3 (0.46) | KCNA3CTSSCTSKCTSBCTSL | |
| SCHEMBL27803999 | 0.80 | HDAC3 (0.42) | KCNA3CTSSCTSKCTSLMEN1 | |
| SCHEMBL27956303 | 0.79 | KMT2A (0.43) | KCNA3CTSSCTSKMEN1NPC1 | |
| SCHEMBL27791882 | 0.78 | KMT2A (0.45) | KCNA3CTSSCTSKMEN1NPC1 | |
| SCHEMBL1951583 | 0.76 | CA12 (0.47) | CTSSCTSKCTSBCTSLMEN1 | |
| SCHEMBL2953752 | 0.76 | CA12 (0.47) | CTSSCTSKCTSBCTSLMEN1 | |
| SCHEMBL5409661 | 0.76 | MEN1 (0.43) | CTSSCTSKCTSBCTSLMEN1 | |
| SCHEMBL1951666 | 0.76 | CA12 (0.47) | CTSSCTSKCTSBCTSLMEN1 | |
| SCHEMBL7872409 | 0.75 | CYP2C19 (0.42) | KCNA3CTSSCTSKMEN1KMT2A | |
| SCHEMBL13567863 | 0.75 | CTSS (0.50) | KCNA3CTSSCTSKCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050250765-A1 | Diazepinones as antiviral agents | CHO HIDETSURA | 2005-11-10 | — | — | US | disclosed |
| US-20040116410-A1 | Diazepinones as antiviral agents | CHO HIDETSURA (JP) | 2004-06-17 | — | — | US | disclosed |
| WO-2002014324-A2 | DIAZEPINONES AS ANTIVIRAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2002-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250765-A1 | Diazepinones as antiviral agents | ZC3HAV1, ECI1, ZC3HAV1L | KCNA3 2125/4885CTSS 2164/4885CTSK 2200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.