Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 11/20 | 0.45 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3651860 | 0.75 | NR3C1 (0.75) | NR3C1PGR | |
| SCHEMBL6320923 | 0.75 | NR3C1 (0.68) | NR3C1PGR | |
| SCHEMBL6320920 | 0.75 | NR3C1 (0.54) | NR3C1PGR | |
| SCHEMBL6314570 | 0.66 | NR3C1 (0.53) | NR3C1PGRALDH1A1 | |
| SCHEMBL4827164 | 0.63 | NR3C1 (0.82) | NR3C1PGR | |
| SCHEMBL3652420 | 0.63 | NR3C1 (0.82) | NR3C1PGR | |
| SCHEMBL3650311 | 0.63 | NR3C1 (0.71) | NR3C1PGR | |
| SCHEMBL4818153 | 0.62 | NR3C1 (0.76) | NR3C1PGR | |
| SCHEMBL3651593 | 0.62 | NR3C1 (1.00) | NR3C1PGR | |
| SCHEMBL4825644 | 0.62 | NR3C1 (0.80) | NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897224-B2 | Quinoline and isoquinoline derivatives, a process for their production and their use as inflammation inhibitors | SCHERING AG (DE) | 2005-05-24 | — | — | US | disclosed |