Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 5/20 | 0.35 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6947441 | 0.86 | PTGES (0.36) | PTGES | |
| SCHEMBL17262847 | 0.75 | PDE8B (0.36) | — | |
| SCHEMBL6326881 | 0.75 | ADORA2A (0.35) | PTGESYTHDC1 | |
| SCHEMBL19872920 | 0.68 | PBK (0.36) | — | |
| SCHEMBL3115347 | 0.66 | PTGES (0.37) | PTGES | |
| SCHEMBL14723131 | 0.66 | AURKA (0.36) | PTGES | |
| SCHEMBL14250446 | 0.66 | MAPK8 (0.34) | — | |
| SCHEMBL27035307 | 0.65 | MAPK8 (0.34) | — | |
| Hydrochloric Acid SCHEMBL30769901 | 0.65 | MAPK8 (0.34) | — | |
| Hydrochloric Acid SCHEMBL30769712 | 0.65 | MAPK8 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050124574-A1 | Purine derivatives | PFIZER INC. | 2005-06-09 | — | — | US | disclosed |
| US-6900309-B1 | Purine derivatives | PFIZER INC (US) | 2005-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124574-A1 | Purine derivatives | ADORA2A, ADORA3, ADORA1 | PTGES 884/4885YTHDC1 1920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.