Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6322165 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9APOLBTSHR | |
| SCHEMBL6323867 | 0.91 | POLB (0.43) | SMN1; SMN2NPC1RAB9APOLBTSHR | |
| SCHEMBL6323870 | 0.91 | POLB (0.43) | SMN1; SMN2NPC1RAB9APOLBTSHR | |
| SCHEMBL6323879 | 0.88 | POLB (0.47) | SMN1; SMN2POLBTSHRHSD17B10MAPT | |
| SCHEMBL6323874 | 0.88 | POLB (0.47) | SMN1; SMN2POLBTSHRHSD17B10MAPT | |
| SCHEMBL6319157 | 0.86 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9AMAPTNR3C1 | |
| SCHEMBL6319153 | 0.86 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9AMAPTNR3C1 | |
| SCHEMBL6321964 | 0.86 | POLB (0.44) | SMN1; SMN2POLBTSHRHSD17B10MAPT | |
| SCHEMBL6321961 | 0.86 | POLB (0.44) | SMN1; SMN2POLBTSHRHSD17B10MAPT | |
| SCHEMBL6320803 | 0.84 | POLB (0.43) | SMN1; SMN2POLBTSHRMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050043371-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-02-24 | — | — | US | disclosed |
| US-20030181726-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2003-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043371-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | ADRB1, ADRB3, ADRB2 | SMN1; SMN2 1593/4885NPC1 4266/4885RAB9A 1231/4885 |
| US-20030181726-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | ADRB1, ADRB3, ADRB2 | SMN1; SMN2 1281/4885NPC1 4169/4885RAB9A 1187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.