Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6202040 | 0.91 | LMNA (0.48) | L3MBTL1POLBNAAAHTTLMNA | |
| SCHEMBL4929013 | 0.80 | CES1 (0.46) | L3MBTL1NAAAHTTLMNACES1 | |
| SCHEMBL8036704 | 0.78 | SCN5A (0.49) | NAAACES1CES2SRCGAA | |
| SCHEMBL4790278 | 0.78 | CES1 (0.47) | L3MBTL1SMN1; SMN2POLBHTTLMNA | |
| SCHEMBL15865137 | 0.77 | SCN5A (0.51) | NAAACES1CES2GAA | |
| SCHEMBL8753891 | 0.77 | SCN5A (0.51) | NAAACES1CES2GAA | |
| SCHEMBL11442119 | 0.77 | SCN5A (0.51) | NAAACES1CES2GAA | |
| SCHEMBL8753682 | 0.77 | SCN5A (0.51) | NAAACES1CES2GAA | |
| SCHEMBL11667545 | 0.77 | SCN5A (0.51) | NAAACES1CES2GAA | |
| SCHEMBL452703 | 0.76 | CES1 (0.49) | L3MBTL1HTTLMNACES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |