Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2123914 | 0.78 | SLC6A9 (0.49) | SLC6A9OPRK1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL2125223 | 0.76 | SLC6A9 (0.48) | SLC6A9OPRK1DRD2DRD3 | |
| SCHEMBL381168 | 0.73 | SLC6A9 (0.40) | SLC6A9OPRK1 | |
| SCHEMBL12881261 | 0.72 | DPP4 (0.41) | OPRK1DRD2DRD4DRD3 | |
| SCHEMBL168288 | 0.70 | SIGMAR1 (0.38) | OPRK1DRD2DRD4DRD3 | |
| SCHEMBL12881251 | 0.69 | CYP3A4 (0.36) | OPRK1 | |
| SCHEMBL771596 | 0.69 | CYP3A4 (0.41) | OPRK1DRD2DRD4DRD3 | |
| SCHEMBL7808275 | 0.69 | SIGMAR1 (0.40) | OPRK1DRD2DRD4DRD3 | |
| SCHEMBL4186582 | 0.69 | SLC6A9 (0.51) | SLC6A9 | |
| SCHEMBL3708922 | 0.69 | SLC6A9 (0.51) | SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419431-A1 | DERIVATIVES OF N-[(7-AZA-BICYCLO[2.2.1]HEPT-1-YL)-ARYL-METHYL]-BENZAMIDE, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-02-22 | — | — | EP | disclosed |
| WO-2010119222-A1 | DERIVATIVES OF N-[(7-AZA-BICYCLO[2.2.1]HEPT-1-YL)-ARYL-METHYL]-BENZAMIDE, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-10-21 | — | — | WO | disclosed |