Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 6/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6320653 | 0.84 | HCAR2 (0.36) | TSHRCES2MAPTHCAR2ALDH1A1 | |
| SCHEMBL5537729 | 0.82 | NAAA (0.54) | NAAAEPHX1TSHRCES2MAPT | |
| SCHEMBL31303206 | 0.81 | MAPT (0.52) | NAAAEPHX1TSHRMAPTHCAR2 | |
| SCHEMBL27437326 | 0.79 | NAAA (0.55) | NAAAEPHX1TSHRMAPTHCAR2 | |
| SCHEMBL19978675 | 0.77 | NAAA (0.53) | NAAAEPHX1TSHRMAPTHCAR2 | |
| SCHEMBL19978677 | 0.77 | NAAA (0.53) | NAAAEPHX1TSHRMAPTHCAR2 | |
| SCHEMBL19978880 | 0.77 | NAAA (0.53) | NAAAEPHX1TSHRMAPTHCAR2 | |
| SCHEMBL1901419 | 0.76 | ALDH1A1 (0.56) | NAAAEPHX1TSHRCES2MAPT | |
| SCHEMBL17770848 | 0.76 | NAAA (0.52) | NAAAEPHX1TSHRCES2MAPT | |
| SCHEMBL13998857 | 0.76 | NAAA (0.52) | NAAAEPHX1TSHRMAPTHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6893861-B1 | Method for producing trifluoro-3(r)-hydroxybutyric acid derivatives | LONZA AG (CH) | 2005-05-17 | — | — | US | disclosed |